Ganglionated plexi ablation to treat exercise-induced vasovagal syncope: A case report

Hong, Xu-Lin; Jiang, Ruhong; Zhu, Jiali; He, Jialin

doi:10.1016/j.hrcr.2020.08.009

Cited by 2 publications

(4 citation statements)

References 15 publications

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“…Consecutive study patients underwent case‐control in a 1:1 fashion using the matching study to GP catheter ablation therapy (ablation group) or guideline‐directed conventional therapy (control group). Ablation group patients underwent selective anatomical catheter ablation of LSGP and RAGP in the left atrium, which was performed according to our ablation protocol, 13 and were not given guideline‐directed conventional therapy including lifestyle management, health education, or physical therapy. Control group patients were given advice for diet, fluid, health education, and physical therapy 1 .…”

Section: Methodsmentioning

confidence: 99%

“…Anatomically guided ablation of the left atrium endocardial left superior ganglionated plexus (LSGP) and right anterior ganglionated plexus (RAGP) were performed according to our ablation protocol (Figure 1). 13 LSGP was located in the superolateral area around the roof of the left superior pulmonary (LSPV) 14 . It could be exposed from the anteroposterior cranial projection.…”

Section: Methodsmentioning

confidence: 99%

“…Ablation group patients underwent selective anatomical catheter ablation of LSGP and RAGP in the left atrium, which was performed according to our ablation protocol, 13…”

Section: Study Populationmentioning

confidence: 99%

“…Three-dimensional models (LSGP) and right anterior ganglionated plexus (RAGP) were performed according to our ablation protocol (Figure 1). 13 LSGP was located in the superolateral area around the roof of the left superior pulmonary (LSPV). 14 Catheter ablation is effectively defined as transient ventricular asystole, atrioventricular block, or R-R interval prolonged >50%.…”

Section: Electrophysiological Study and Gp Ablation Proceduresmentioning

confidence: 99%

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Selective anatomical catheter ablation of left atrial ganglionated plexus for vasovagal syncope: Left superior and right anterior ganglionated plexus ablation

Jin

Liu

Jiang

et al. 2023

Pacing Clinical Electrophis

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BackgroundVasovagal syncope (VVS) is one of the most common causes of syncope. Traditional treatment has not achieved satisfactory results. The purpose of this study was to assess the feasibility and efficacy of selective anatomical catheter ablation of left atrial ganglionated plexus (GP) as a therapeutic strategy for the patients of symptomatic VVS.MethodsA total of 70 patients with at least once recurrent syncopal episode of VVS with a positive head‐up tilt test were enrolled. They were divided into GP ablation group and control group. Patients in GP ablation group received anatomical catheter ablation of left superior ganglionated plexus (LSGP) and right anterior ganglionated plexus (RAGP). Patients in the control group were guideline‐directed conventional therapy. The primary endpoint was VVS recurrences. The secondary endpoint was the recurrence of syncope and prodrome events.ResultsThere were no statistical differences in clinical characteristics between the ablation group (n = 35) and the control group (n = 35). Over a follow‐up of 12 months, the ablation group had significantly lower syncope recurrence compared with the control group (5.7% vs. 25.7%, p = .02), and the ablation group had significantly lower syncope and prodrome recurrence compared with the control group (11.4% vs. 51.4%, p < .001). In GP ablation, 88.6% of the patients showed significant vagal response during LSGP ablation, and 88.6% of the patients showed significantly increased heart rate during RAGP ablation.ConclusionsFor patients with recurrent VVS, selective anatomical catheter ablation of LSGP and RAGP is superior to conventional therapy in reducing syncope recurrence.

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Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

“…Ablation group patients underwent selective anatomical catheter ablation of LSGP and RAGP in the left atrium, which was performed according to our ablation protocol, 13…”

Section: Study Populationmentioning

confidence: 99%

Section: Electrophysiological Study and Gp Ablation Proceduresmentioning

confidence: 99%

See 2 more Smart Citations

Selective anatomical catheter ablation of left atrial ganglionated plexus for vasovagal syncope: Left superior and right anterior ganglionated plexus ablation

Jin

Liu

Jiang

et al. 2023

Pacing Clinical Electrophis

View full text Add to dashboard Cite

show abstract

Selective anatomical catheter ablation of left atrial ganglionated plexus for vasovagal syncope: left superior and right anterior ganglionated plexus ablation

Jin

Liu

Jiang

et al. 2022

Preprint

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Background Vasovagal syncope (VVS) is one of the most common causes of syncope. Traditional treatment has not achieved satisfactory results. The purpose of this study was to assess the feasibility and efficacy of selective anatomical catheter ablation of left atrial ganglionated plexus (GP) as a therapeutic strategy for the patients of symptomatic VVS. Methods A total of 70 patients with at least once recurrent syncopal episodes of VVS with positive head-up tilt test were enrolled. They were divided into GP ablation group and control group. Patients in GP ablation group were received anatomical catheter ablation of left superior ganglionated plexus (LSGP) and right anterior ganglionated plexus (RAGP). Patients in control group were guideline-direted conventional therapy. The primary endpoint was VVS recurrences. The secondary endpoint was recurrence of syncope and prodrome events. Results There were no statistical differences in clinical characteristics between the ablation group (n = 35) and control group (n = 35). Over a follow-up of 12 months, ablation group had significantly lower syncope recurrence compared with control group (5.7% vs. 25.7%, P = 0.02), and ablation group had significantly lower syncope and prodrome recurrence compared with control group (11.4% vs. 51.4%, P < 0.001). In GP ablation, 88.6% of the patients showed significant vagal response during LSGP ablation, and 88.6% of the patients showed significant increased heart rate during RAGP ablation. Conclusions For patients with recurrent VVS, selective anatomical catheter ablation of LSGP and RAGP is superior to conventional therapy in reducing syncope recurrence.

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Ganglionated plexi ablation to treat exercise-induced vasovagal syncope: A case report

Cited by 2 publications

References 15 publications

Selective anatomical catheter ablation of left atrial ganglionated plexus for vasovagal syncope: Left superior and right anterior ganglionated plexus ablation

Selective anatomical catheter ablation of left atrial ganglionated plexus for vasovagal syncope: Left superior and right anterior ganglionated plexus ablation

Selective anatomical catheter ablation of left atrial ganglionated plexus for vasovagal syncope: left superior and right anterior ganglionated plexus ablation

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