In this paper, we study the topological properties and the gap sequences of Bedford-McMullen sets. First, we introduce a topological condition and a geometric condition: component separation condition (CSC) and exponential rate condition (ERC). Then we prove that the CSC implies the ERC, while both of them are sufficient conditions for obtaining the asymptotic estimate of gap sequences of Bedford-McMullen sets. Finally, we explore topological properties of Bedford-McMullen sets, and prove that all nonlinear Bedford-McMullen sets satisfy the CSC, which implies that the asymptotic estimate of gap sequences holds without any artificial restriction.