Gaps in cardiovascular medication taking

Abstract

Major treatment gaps occur frequently, even in carefully selected ambulatory populations, and generally escape detection. The compliance patterns and gaps may contribute to reported excesses of cardiovascular morbidity and mortality.

Adherence to topical therapy decreases during the course of an 8-week psoriasis clinical trial: Commonly used methods of measuring adherence to topical therapy overestimate actual use

“…However, previous research has not found consistent factors that predict adherence. 15,16 Our study also determined that age was a significant predictor of adherence, with older age predicting better adherence. Notably, however, our study lacks the extreme category of elderly, therefore, the association of greater age and better adherence may not hold for those older than 70 years.…”

Levodopa dosage determines adherence to long-acting dopamine agonists in Parkinson's disease

“…Several methods have been used to assess the degree of adherence to treatment, including self-report measures, direct pill counts, electronic monitoring of pill counts (bottle opening electronic recordings) and biological methods [12]. All of them are imperfect and tend to overestimate treatment compliance [13][14][15][16][17][18][19]. Direct pill counts can identify adherence problems when bottles with an excessive number of pills are returned, but participants may discard drugs and return empty containers.…”

Concordance of Adherence Measurement Using Self-Reported Adherence Questionnaires and Medication Monitoring Devices

“…Of the 41 actual articles, the disease states were as follows: HIV (n = 18; 43.9%), [11][12][13][14][15][16][17][18]20,26,28,31,33,[35][36][37]43,44] psychotic disorders (n = 4; 9.8%), [29,34,41,49] cardiovascular diseases (n = 3; 7.3%), [32,38,50] hypertension (n = 3; 7.3%), [23,24,27] transplant (n = 2; 4.9%) [21,30] and diabetes mellitus (n = 2; 4.9%). [19,46] The sample sizes ranged from 5 to 1021 (median = 61).…”