Gardner’s syndrome: A case report and review of the literature

Fotiadis, C; Tsekouras, DK; Antonakis, Pantelis; Sfiniadakis, J; Genetzakis, Michael; Gc, Zografos

doi:10.3748/wjg.v11.i34.5408

Cited by 82 publications

(110 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Fotiadis C et al, [6], opined that DT in the abdominal wall is easier to remove and recurrence rates are lower when compared to mesenteric or retroperitoneal DT. Despite radical surgery and adjuvant radiotherapy 25%-50% recur [1].…”

Section: Discussionmentioning

confidence: 99%

Mesenteric Fibromatosis (Desmoid Tumour) - A Rare Case Report

2014

JCDR

View full text Add to dashboard Cite

A 29-year-old male presented with complaints of swelling in the right side of umbilicus for six months associated with dull ache for two months. It was gradually increasing in size and there was no other symptom. There was no significant past or family history.A globular intraperitoneal lump approx 5x4 cm was found in umbilical region which was firm, mobile, and mildly tender with smooth surface and margin, no fixity but not moving with respiration. Ultrasonography (USG) of whole abdomen showed it as intra abdominal abscess or cyst. Fine needle aspiration cytology revealed a few monolayered clusters of colonic mucosal cells, some muscle fibres and mucin strings in the background of blood with no atypical or malignant cells. Contrast enhanced computerized tomography Revealed an oval hypodense (+25 HU) and mildly enhancing (+46 HU) focal lesion in intraperitoneal cavity with retroperitoneal extension suggestive of leiomyoma or GastroIntestinal Stromal Tumour. Colonoscopy and endoscopy showed no polyps.Exploratory laparotomy revealed a mass 6x5x4 cm [Table/ Fig-1] in ileal mesentery. It was excised along with 20cm of ileum and end to end anastomosis in two layers.Histopathologically [Table/ Fig-2], a lesion in the subepithelium composed of cells with blunt ended nuclei arranged in sheets, fascicles, whorl and haphazard patterns was found. Hyalinised capillaries were interspersed with focal lymphocytic infiltration and cells with moderate nuclearr atypia in peripheral areas characterized MF. Postoperative days were uneventful and discharged on 10 th day. Adjuvant radiotherapy (50 Gy) was given to our patient in the post operative period. Follow up for three years which included USG abdomen and colonoscopy didn't reveal any new pathological lesions. DISCUSSIONThe term 'desmoid' was coined by Muller in 1838 and was derived from Greek word 'desmos' meaning band or tendon [1]. These are rare tumours, arising from musculo-aponeurotic elements accounting for about 0.03% of all neoplasm and 3.5% of all fibrous tissue neoplasm [2]. It is commonly seen in reproductive years of A 29-year-old male presented with a swelling on the right side of the umbilicus for six months and dull aching pain for two months. Fine needle aspiration cytology, ultrasonography, contrast enhanced computerized tomography findings were inconclusive. After Exploratory laparotomy, a mass approx 6x5x4 cm in ileal mesentery was identified and excised along with 20cm of ileum. End to end anastomosis was done and specimen was sent for histopathology which confirmed the diagnosis of MF. Considering the rarity of this tumour and difficulties in diagnostic and therapeutic ambit, we believe it is justified to describe this case which came to our observation.women, often during and after pregnancy [1,3]. Desmoid tumours (DT) are histologically benign, but they may show local recurrence after excision [3].

show abstract

Section: Discussionmentioning

confidence: 99%

Mesenteric Fibromatosis (Desmoid Tumour) - A Rare Case Report

2014

JCDR

View full text Add to dashboard Cite

show abstract

“…FAP nedeniyle IRA uygulananlarda yıllık rektoskopi, IPAA uygulananlarda yıllık proktoskopi kontrolü yapılması gerekmektedir. 5,6 Cerrahi tedavinin morbidite ve mortalitesi nedeniyle adenomatöz poliplerin malign potansiyelini azaltabilecek ilaçlar araştırılmaya başlanmıştır. Sulindak ve diğer NSAI ilaçlarla polip sayısı ve boyutunda azalma olduğu gösterilmiştir.…”

Section: Discussionunclassified

Adenocarcinoma arising in adenomatous polyposis coli

Yılmaz¹,

Özden²

2014

Sakarya Med J

View full text Add to dashboard Cite

Familyal adenomatöz polipozi koli (FAP) özellikle kolon epitelinde çok sayıda polip oluşumuyla karakterize genetik geçişli bir sendromdur. Tedavi edilmediği takdirde kanser gelişme riski giderek artmaktadır. Rektal kanama ve karın ağrısı gibi aşikar semptomlardan dolayı hastalar genellikle erken tanı almaktadır. Biz burada acil serviste tanı konulmuş olan malign transformasyon göstermiş bir FAP olgusunu sunmaktayız. Özet AbstractOlgu Sunumu / Case Reports

show abstract

“…Besides these manifestations, thyroid cancers and central nervous system tumors were also reported in FAP [11]. Although associations of FAP and DT involving mesentery, retroperitoneum, abdominal wall, liver, pelvis, lumbar region, latissimus dorsi muscle, and neck were defined [7,12,13,14,15,16,17,18], only 1 pediatric case of DT with FAP had been reported previously [6]. Cytogenetic analysis of that case demonstrated loss of chromosome region 5 (q21q22) [6], but we did not have the chance to examine our patient and family for this highly probable genetic abnormality.…”

Section: Discussionmentioning

confidence: 99%

Intracranial Desmoid Tumor with Familial Adenomatous Polyposis Coli

et al. 2008

View full text Add to dashboard Cite

Intracranial desmoid tumors are extremely rare. The association of desmoid tumors with familial adenomatous polyposis coli was reported previously, with the tumors involving trunk and extremities. We report a 3.5-year-old girl with intracranial desmoid tumor with familial adenomatous polyposis coli. This condition in a child is rarely reported. Follow-up of the patient after cranial surgery and of the family for this premalignant inherited condition is necessary.

show abstract

Gardner’s syndrome: A case report and review of the literature

Cited by 82 publications

References 22 publications

Mesenteric Fibromatosis (Desmoid Tumour) - A Rare Case Report

Mesenteric Fibromatosis (Desmoid Tumour) - A Rare Case Report

Adenocarcinoma arising in adenomatous polyposis coli

Intracranial Desmoid Tumor with Familial Adenomatous Polyposis Coli

Contact Info

Product

Resources

About