Gas Chromatographic and Mass Spectroscopic (GC-MS) Analysis of Rhizome of &lt;i&gt;Acorus Calamus&lt;/i&gt; Linn. for Identification of Potent Antimicrobial Bio-active Compounds

Srinivasu, P.; Kumar, Jyoti

doi:10.3329/jsr.v13i1.48452

Cited by 4 publications

(1 citation statement)

References 19 publications

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“…[28] It is a 5α-reductase inhibitor, prevents inflammation, repels insects, and has hypocholesterolemic effects. [29] 9-Octadecenoic acid (Z)-,…”

Section: Analysis Of Extracts For Their Secondary Metabolites By Gas ...mentioning

confidence: 99%

Comparison of the Anti-asthmatic Potential of Himalayan Plants Lonicera obovata Royle and Morina longifolia Wall: An in vivo Study

Boora¹,

Puri²,

Rani³

et al. 2023

Pharmacogn. Res.

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Background: Asthma is a very common and chronic disease in which there is an inflammation of the lungs. Inflammatory airways and narrowing, spasms, over-secretion of mucus, bronchoconstriction, and eosinophilic airway inflammation are generally seen in the asthmatic condition. Globally, its prevalence is rising constantly. The extracts of Lonicera obovata and Morina longifolia of the Caprifoliaceae family were traditionally used by the Himalayan local people to treat asthmatic and inflammatory conditions. Objectives: The goal of this experimental study was to identify the phytochemicals of the plants through GC-MS. To investigate and compare the anti-asthmatic potential of methanolic whole plant extracts of L. obovata and methanolic root extracts of M. longifolia through in-vivo experiments. Materials and Methods: The anti-asthmatic potential of extracts was determined by the method of leukocytosis and eosinophilia induced by milk in the Swiss albino mice model. Results: Various secondary active phytoconstituents were detected through the GC-MS screening method, some of which have anti-allergic (anti-asthmatic) and antihistaminic properties. The in vivo experiment result showed that in the case of increased leukocyte count, M. longifolia shows better results than L. obovata, and in the case of increased eosinophil count, L. obovata shows better results than M. longifolia to reduce the increased count. Conclusion:The anti-asthmatic potential of plant extracts could be due to the presence of the phytoconstituents like 1-Monolinoleoylglycerol trimethylsilyl ether in the L. obovata extracts and Octadec-9-enoic acid and Cis-vaccenic acid in both L. obovata and M. longifolia extracts. Hence, through the experiments, the unexplored anti-asthmatic properties were revealed and justifies the traditional usage of both plants to treat asthma.

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“…[28] It is a 5α-reductase inhibitor, prevents inflammation, repels insects, and has hypocholesterolemic effects. [29] 9-Octadecenoic acid (Z)-,…”

Section: Analysis Of Extracts For Their Secondary Metabolites By Gas ...mentioning

confidence: 99%

Comparison of the Anti-asthmatic Potential of Himalayan Plants Lonicera obovata Royle and Morina longifolia Wall: An in vivo Study

Boora¹,

Puri²,

Rani³

et al. 2023

Pharmacogn. Res.

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Synthesis and characterization of cry protein coated zinc oxide nanocomposites and its assessment against bacterial biofilm and mosquito vectors

Vinotha

Yazhiniprabha

Jeyavani

et al. 2022

International Journal of Biological Macromolecules

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GC-MS Profiling of Reproductive Stage Withania somnifera for Antimicrobial and Anticancer Phytochemicals

Lingfa

Ankanagari

2023

Biomed. Pharmacol. J.

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Withanias omnifera also known as Indian ginseng is commonly found in India and other Southeast Asian countries. Various parts of this plant have been used as herbal medicine to treat a variety of diseases. However, there is a lacuna in the profiling of phytochemical constituents present in the different parts of the plant at reproductive stage. To identify phytochemicals present in the methanolic extracts of leaf, root, and stem parts of W. somnifera at reproductive stage using GC-MS analysis. Methods: The airdried parts of plant (leaf, stem and root) were extracted with methanol and concentrated under reduced pressure at 40°C using a rotary evaporator. The GCMSQP2010, Shimadzu, Kyoto, Japan with headspace sampler (AOC-20s) and autoinjector (AOC-20i), was used for sample analysis. The phytochemicals were identified with the database provided by National Institute Standard and Technology (NIST11LIB). The GC-MS analysis of leaf, root, and stem methanolic extracts of W. somnifera, revealed a total of eighty-two unique phytochemical peaks in the reproductive stage of the plant. Phytochemicals with antimicrobial and anticancer properties were identified in all the parts. In leaf, 2-pentanone, 5-chloro- was found to be most abundant and 2,5-dimethoxy-4-propoxy-. beta.-methyl-.beta.-nitrostyrene least abundant with antimicrobial nature, whereas, benzene, 1,1'-(1,2-ethenediyl)bis[2-methyl- was found to be most abundant and dibenzo[a,e]cyclooctene, 5,6,11,12-tetrahydro- least with anticancer property. In roots, the most abundant was benzoic acid, 3-methyl-2-trimethylsilyloxy-, trimethylsilyl ester and tris(trimethylsilyl)hydroxylamine the least abundant were identified to be antimicrobial, whereas high abundance uleine and low abundance 2-{4-[2-(4-methoxymethylphenyl)vinyl]phenyl}propan-2-olwere identified to be anticancer. In stem, acetohydroxamic acid was found to be most abundant and trans2,3,6-trimethoxy-b-methyl-b-nitrostyrene least abundant for antimicrobial nature, whereas 3-acetoxy-2,3'-bibenzo[b]thiophene was found to be anticancer phytochemical. In this study, phytochemicals with antimicrobial and anticancer properties were identified in leaf, root and stem parts of W. somnifera at reproductive stage.

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Gas Chromatographic and Mass Spectroscopic (GC-MS) Analysis of Rhizome of <i>Acorus Calamus</i> Linn. for Identification of Potent Antimicrobial Bio-active Compounds

Cited by 4 publications

References 19 publications

Comparison of the Anti-asthmatic Potential of Himalayan Plants Lonicera obovata Royle and Morina longifolia Wall: An in vivo Study

Comparison of the Anti-asthmatic Potential of Himalayan Plants Lonicera obovata Royle and Morina longifolia Wall: An in vivo Study

Synthesis and characterization of cry protein coated zinc oxide nanocomposites and its assessment against bacterial biofilm and mosquito vectors

GC-MS Profiling of Reproductive Stage Withania somnifera for Antimicrobial and Anticancer Phytochemicals

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