Gas chromatographic determination of fatty acid composition in breast milk of mothers with different health conditions

Zhang, M.; Sarkadi, Livia Simon; Üveges, M.; Tormási, Judit; Benes, Eszter; Vass, Réka A.; Vari, Sandor G.

doi:10.1556/066.2022.00120

Cited by 3 publications

(1 citation statement)

References 16 publications

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“…Breastfeeding and the unique composition of human milk have been associated with numerous long-term health benefits for infants, including a reduced risk of certain infections, allergies, and chronic diseases later in life [ 51 , 52 , 53 ]. Maternal diet influences the composition of BM [ 43 , 54 ] and the fetal outcome of the pregnancy [ 42 ].…”

Section: Discussionmentioning

confidence: 99%

Effect of Holder Pasteurization, Mode of Delivery, and Infant’s Gender on Fatty Acid Composition of Donor Breast Milk

Vass,

Zhang,

Simon Sarkadi

et al. 2024

Nutrients

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Breast milk (BM) plays a crucial role in providing essential fatty acids (FA) and energy for the growing infant. When the mother’s own BM is not available, nutritional recommendations suggest donor milk (DM) in clinical and home practices. BM was collected from a variety of donor mothers in different lactation stages. Holder pasteurization (HoP) eliminates potential contaminants to ensure safety. FA content of BM samples from the Breast Milk Collection Center of Pécs, Hungary, were analyzed before and after HoP. HoP decreases the level of C6:0, C8:0, C14:1n-5c, C18:1n-9c, C18:3n-6c, C18:3n-3c, and C20:4n-6c in BM, while C14:0, C16:0, C18:1n-9t, C22:0, C22:1n-9c, C24:0, C24:1n-9c, and C22:6n-3c were found in elevated concentration after HoP. We did not detect time-dependent concentration changes in FAs in the first year of lactation. BM produced for girl infants contains higher C20:2n-6c levels. In the BM of mothers who delivered via cesarean section, C12:0, C15:0, C16:0, C17:0, C18:0, C18:1n-9t, C22:1n-9c levels were higher, while C18:2n-6c, C22:0, C24:0, and C22:6n-3c concentrations were lower compared to mothers who gave birth spontaneously. FAs in BM are constant during the first year of lactation. Although HoP modifies the concentration of different FAs, pasteurized DM provides essential FAs to the developing infant. Current data providing information about the FA profile of BM gives origination to supplementation guidelines.

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Section: Discussionmentioning

confidence: 99%

Effect of Holder Pasteurization, Mode of Delivery, and Infant’s Gender on Fatty Acid Composition of Donor Breast Milk

Vass,

Zhang,

Simon Sarkadi

et al. 2024

Nutrients

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Quality Assessment of Reconstructed Cow, Camel and Mare Milk Powders by Near-Infrared Spectroscopy and Chemometrics

Majadi,

Barkó,

Varga-Tóth

et al. 2024

Molecules

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Milk powders are becoming a major attraction for many industrial applications due to their nutritional and functional properties. Different types of powdered milk, each with their own distinct chemical compositions, can have different functionalities. Consequently, the development of rapid monitoring methods is becoming an urgent task to explore and expand their applicability. Lately, there is growing emphasis on the potential of near-infrared spectroscopy (NIRS) as a rapid technique for the quality assessment of dairy products. In the present work, we explored the potential of NIRS coupled with chemometrics for the prediction of the main functional and chemical properties of three types of milk powders, as well as their important processing parameters. Mare, camel and cow milk powders were prepared at different concentrations (5%, 10% and 12%) and temperatures (25 °C, 40 °C and 65 °C), and then their main physicochemical attributes and NIRS spectra were analyzed. Overall, high accuracy in both recognition and prediction based on type, concentration and temperature was achieved by NIRS-based models, and the quantification of quality attributes (pH, viscosity, dry matter content, fat content, conductivity and individual amino acid content) also resulted in high accuracy in the models. R2CV and R2pr values ranging from 0.8 to 0.99 and 0.7 to 0.98, respectively, were obtained by using PLSR models. However, SVR models achieved higher R2CV and R2pr values, ranging from 0.91 to 0.99 and 0.80 to 0.99, respectively.

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Changes in the Fatty Acid Profile of Lactating Women Living in Poland—A Comparison with the Fatty Acid Profile of Selected Infant Formulas

Purkiewicz,

Pietrzak-Fiećko

2024

Nutrients

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The present study examined the fatty acid content of human milk from Polish women living in the Warmia and Mazury region with regard to different lactation periods and compared it with the fatty acid content of selected infant formulas. The analysis included samples of breast milk—colostrum (n = 21), transitional milk (n = 26), and mature milk (n = 22). Fat was extracted using the Rose-Gottlieb method, and the fatty acid profile was determined by gas chromatography with a flame ionization detector (FID). The proportion of SFAs (saturated fatty acids) > MUFAs (monounsaturated fatty acids) > PUFAs (polyunsaturated fatty acids) was determined in each fraction of breast milk and infant formula. Palmitic, oleic, and linoleic acids predominated in breast milk and infant formulas. Colostrum contained lower contents of selected SFAs (caprylic, capric, lauric) and higher contents of selected MUFAs (ercucic) and PUFAs (arachidonic and docosahexaenoic) (p < 0.05) relative to transitional and mature milk. Infant formulas were distinguished from human milk in terms of their SFA (caproic, caprylic, lauric, arachidic), MUFA (oleic), and PUFA (linoleic, α-linoleic) content. It should be noted that infant formulas contained significantly lower trans fatty acid (TFA) content—more than thirty-six and more than nineteen times lower than in human milk. Furthermore, human milk contained branched-chain fatty acids (BCFAs) at 0.23–0.28%, while infant formulas contained only trace amounts of these acids. The average ratio of n-6 to n-3 fatty acids for human milk was 6.59:1 and was close to the worldwide ratio of 6.53 ± 1.72:1. Both principal component analysis (PCA) and cluster analysis (CA) indicated significant differences in the fatty acid profile relative to lactation and a different profile of infant formulas relative to breast milk.

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Gas chromatographic determination of fatty acid composition in breast milk of mothers with different health conditions

Cited by 3 publications

References 16 publications

Effect of Holder Pasteurization, Mode of Delivery, and Infant’s Gender on Fatty Acid Composition of Donor Breast Milk

Effect of Holder Pasteurization, Mode of Delivery, and Infant’s Gender on Fatty Acid Composition of Donor Breast Milk

Quality Assessment of Reconstructed Cow, Camel and Mare Milk Powders by Near-Infrared Spectroscopy and Chemometrics

Changes in the Fatty Acid Profile of Lactating Women Living in Poland—A Comparison with the Fatty Acid Profile of Selected Infant Formulas

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