1982
DOI: 10.1002/bms.1200090402
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Gas chromatographic mass spectrometric determination of myo-inositol in humans utilizing a deuterated internal standard

Abstract: The isotopic dilution technique was used for determining the content of myo-inositol in human urine, plasma and haemolysed erythrocyte samples. A deuterated myo-inositol, synthesized from inosose-2 by base-catalysed exchange of hydrogens by deuterium, followed by reduction of the inosose with 2H2, was added as internal standard to the samples at an early stage in the analytical procedure. After separation and derivatization to the hexa-acetate, the gas chromatographic mass spectrometric analysis was carried ou… Show more

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Cited by 12 publications
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