“…In previous studies, we postulated that these cholinergic gasotransmitters may be a part of the system commonly known in eastern medicine and philosophy as a yin/yang system. The O 2 stimulation metabolism factor may be recognized as a yang factor (hot, accelerating, enhancing), contrary to CO, NO, and H 2 S inhibiting metabolism factors, which may be recognized as yin factors (cold, inhibiting, weakening) (Gajewski et al, 2006;Gajewski et al, 2013, for review), see Figure 1.…”