Gastric and colonic metastases from primary lung adenocarcinoma: A case report and review of the literature

Abstract

Abstract. Lung cancer is one of the leading causes of cancer-related mortality worldwide. Gastrointestinal metastasis from primary lung cancer is rare. Only a few reports have been published and the majority of described metastatic sites involved the small intestine. In the present study, we report the first case of primary lung adenocarcinoma with both gastric and colonic metastases. We also review the published literature of primary lung cancer with gastrointestinal metastasis.

Bowel obstruction caused by colonic metastasis of lung adenocarcinoma: a case report and literature review

“…Lung adenocarcinoma had the second highest potential for colonic metastasis [10, 36–44, 52]. Abdominal pain due to intestinal tract obstruction was the most frequent initial clinical symptom of metastatic colon cancer from primary malignant lung neoplasms [19, 25, 29, 32, 33, 37, 38, 40, 43, 44, 52, 53]. Bloody stool due to either melena or hematochezia was also a common chief complaint [5, 10, 17, 31, 35, 48, 56].…”

What is the cause of this synchronous palpable abdominal mass in a woman recently diagnosed with lung cancer as demonstrated in Figure 1?

“…1). Immunohistochemistry confirmed this submucosal lesion was consistent with a metastatic tumor deposit from the known lung primary as biopsies were TTF-1 and CK7 positive (Figs 2 and 3) [1,2].…”

A Rare Cause of Acute Abdomen: Small Intestine Perforation Due to Metastasis of Lung Cancer

“…Pathological flourodeoxyglucose uptake in the region fitting ileum on positron emission tomography was helpful reaching the diagnosis. It was not clear whether the lesion was a primary tumor of the gastrointestinal tract or a metastatic lesion (19). Diagnosis was established later on by immunohistochemical examination of the specimen.…”