Gastric cancer after mini‐gastric bypass surgery: A case report and literature review

Abstract

Gastric cancer in the stomach after Roux-en-Y gastric bypass or mini-gastric bypass is rare, but a few cases have been reported since 1991, when the first case emerged. According to the literature, the interval between bypass surgery and the diagnosis of cancer ranged from 1 to 22 years. Given the difficulty of monitoring a bypassed stomach, the potential for gastric cancer must be considered, especially in countries with high incidence of this cancer. The literature reported the first case in the Asia-Pacific region - a woman developed advanced gastric cancer in her stomach 9 years after laparoscopic mini-gastric bypass for morbid obesity.

Laparoscopic One-Anastomosis Gastric Bypass: Technique, Results, and Long-Term Follow-Up in 1200 Patients

“…The only case of cancer reported thus far also originated in the excluded stomach in an Asian patient 9 years after MGB [68]. In spite that in vitro bile in the esophagus can stimulate production of inflammatory mediators and lead to changes in genetic expression to intestinal metaplasia [55], clinical studies have not demonstrated an association between gastric bile and Barrett’s esophagus [69].…”

Medium-Term Results of Laparoscopic Sleeve Gastrectomy: a Matched Comparison with Gastric Bypass

“…However, given the similar weight loss efficacies and the lower risk of surgical complications and long-term micronutrient deficiencies of LSG, we expect that LSG will be the first choice bariatric surgery in the future. Another important advantage of LSG compared to RYGB or SAGB is the avoidance of the risk of gastric cancer that arises from the excluded remnant stomach [25]. RYGB or SAGB precludes the option of screening the stomach and raises strong concerns in countries with high incidences of gastric cancer, such as countries in Asia, South American, and some parts of Europe.…”

The Name of Mini Gastric Bypass

“…This is a question that ultimately only time can answer, but it is worth noting that in scientific literature, there is only one published report of a cancer after MGB [9] and, even in this patient, cancer was not in the part of the stomach in contact with bile (gastric pouch). This patient developed gastric cancer in her bypassed stomach 9 years after her MGB.…”