2015
DOI: 10.1016/j.gtc.2015.05.009
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Gastric Cancer Risk in Patients with Helicobacter pylori Infection and Following Its Eradication

Massimo Rugge
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Cited by 25 publications
(23 citation statements)
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“…Helicobacter pylori eradication could almost completely prevent the occurrence of intestinal‐type gastric cancer if gastric mucosa atrophy and/or intestinal metaplasia is not present; however, it is not sufficient to completely eliminate this risk when gastric mucosal atrophy and/or intestinal metaplasia is present . Therefore, these individuals must be followed up.…”
Section: H Pylori Infection and Gastric Cancermentioning
confidence: 99%
“…Helicobacter pylori eradication could almost completely prevent the occurrence of intestinal‐type gastric cancer if gastric mucosa atrophy and/or intestinal metaplasia is not present; however, it is not sufficient to completely eliminate this risk when gastric mucosal atrophy and/or intestinal metaplasia is present . Therefore, these individuals must be followed up.…”
Section: H Pylori Infection and Gastric Cancermentioning
confidence: 99%
“…Hoy en día, el mecanismo oncogénico es entendido por la colonización de HP sobre el epitelio gástrico, produciendo una respuesta inflamatoria local y sistémica, lo que conduce a la conocida cascada de gastritis aguda, gastritis crónica, gastritis crónica atrófica, metaplasia intestinal y displasia, considerándose éstas tres últimas como lesiones premalignas 15 . Estudios recientes han logrado demostrar reducción en la incidencia de cáncer gástrico mediante la erradicación de HP a nivel poblacional, que tiene mayor efecto en zonas de mayor incidencia de cáncer gástrico [16][17][18][19] . Por otro lado, HP se ha relacionado con úlcera péptica gastroduodenal, linfoma gástrico, dispepsia, halitosis 20 , hiperé-mesis gravídica 6 , anemia ferropénica idiopática y púrpura trombocitopénico idiopático.…”
Section: Disminución En La Frecuencia De Infección Por Helicobacter Punclassified
“…Infection with Helicobacter pylori (H pylori), a bacterium that frequently colonizes the human stomach, is a strong and causal risk factor for peptic ulcer disease and gastric cancer [1][2][3]. Worldwide, 95% of duodenal and 70% of gastric ulcers are associated with H pylori [4].…”
Section: Introductionmentioning
confidence: 99%