Gastric carcinoma in patients over 70 years of age

Abstract

The clinicopathological features and prognosis of gastric cancer in 344 patients aged 70 years or older who underwent gastrectomy between 1965 and 1990 were determined. Over the years the mean size of the tumour decreased, differentiated tumour tissue was more common, depth of penetration was less prominent, lymphatic and vascular involvement was less frequent, and the rate of lymph node metastasis and peritoneal dissemination decreased. Extensive lymph node dissection was more frequently carried out and the rate of curative resection rose. Survival rates improved with early detection of gastric cancer and there was no increase in operative morbidity and mortality rates. As age alone is not a contraindication to surgery for patients with gastric carcinoma, early detection of the lesion and surgical treatment are expected to increase the survival of elderly patients with this malignancy.

Estimation of Hazard Function and its Associated Factors in Gastric Cancer Patients using Wavelet and Kernel Smoothing Methods

“…Although in some studies, it proved that age is a significant factor in lifetime (Matley et al, 1988;Mitsudomi et al, 1989;Arveux et al, 1992;Maehara et al, 1995;Haugstvedt et al, 1993;Bucchi et al, 2004;Enzinger and Mayer, 2004;Saidi et al, 2004) there was no significant relationship between age and the lifetime in this study but, in some other studies there was shown that there is not a significant relationship between age and the lifetime (Khedmat et al, 2007;Biglarian et al, 2009;Roshanaei et al, 2010).…”

Increased proliferative activity caused by loss of p21WAF1/CIP1 expression and its clinical significance in patients with early‐stage gastric carcinoma

“…1,2 However, recurrences are likely to take on a variety forms, even after patients undergo curative resection. 3,4 In a retrospective study by Ichiyoshi et al 3 that reported on 503 patients with early-stage gastric carcinoma, 17 patients had died of disease recurrence.…”

Recurrences and related characteristics of gastric cancer

“…With emphasis on early diagnosis and detection of gastric cancer, prophylactic lymph node dissection and postoperative chemotherapy, the prognosis of patients with gastric cancer has improved (Maehara et al, , 1995a. However, recurrences are likely to take on a variety of forms and in different organs, even after curative resection of a gastric cancer (Baba et al, 1989;Ichiyoshi et al, 1990;Moriguchi et al, 1992a).…”