Gastric Carcinoma in Young Adults

Bedikian, Agop Y.; Khankhanian, Nayereh; Heilbrun, Lance K.; Bodey, Gerald P.; Stroehlein, John R.; Valdivieso, Manuel

doi:10.1097/00007611-197906000-00007

Cited by 25 publications

(26 citation statements)

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“…Median patient delay ranged from 2 weeks to 7.5 months (Bedikan et al, 1979;Mikulin and Hardcastle, 1987;Zilling et al, 1990;Haugstvedt et al, 1991;Wile et al, 1993;Porta et al, 1996;Martin et al, 1997;Mariscal et al, 2001;Irving et al, 2002;Look et al, 2003) and practitioner delay from zero to just under 9 months (Mikulin and Hardcastle, 1987;Zilling et al, 1990;Haugstvedt et al, 1991;Jones and Dudgeon, 1992;Martin et al, 1997;Mariscal et al, 2001;Irving et al, 2002;Look et al, 2003).…”

Section: Delay Intervalsmentioning

confidence: 99%

“…Ethnicity was Delay in diagnosis of upper GI cancers S Macdonald et al associated with reduced delay (Wile et al, 1993), while lower socioeconomic status (Hackett et al, 1973;Mikulin and Hardcastle, 1987;Porta et al, 1996) was associated with increased delay. By and large, sex had no impact on delay (MacAdam, 1979;Mikulin and Hardcastle, 1987;Porta et al, 1996;Mariscal et al, 2001), whereas the evidence presented for education level (Porta et al, 1996;Mariscal et al, 2001) and age was inconclusive (Bedikan et al, 1979;MacAdam, 1979;Mikulin and Hardcastle, 1987;Zilling et al, 1990;Porta et al, 1996;Mariscal et al, 2001;Look et al, 2003) (Table 2).…”

Section: Factors Influencing Patient Delaymentioning

confidence: 99%

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Systematic review of factors influencing patient and practitioner delay in diagnosis of upper gastrointestinal cancer

et al. 2006

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As knowledge on the causation of cancers advances and new treatments are developed, early recognition and accurate diagnosis becomes increasingly important. This review focused on identifying factors influencing patient and primary care practitioner delay for upper gastrointestinal cancer. A systematic methodology was applied, including extensive searches of the literature published from 1970 to 2003, systematic data extraction, quality assessment and narrative data synthesis. Included studies were those evaluating factors associated with the time interval between a patient first noticing a cancer symptom and presenting to primary care, between a patient first presenting to primary care and being referred to secondary care, or describing an intervention designed to reduce those intervals. Twenty-five studies were included in the review. Studies reporting delay intervals demonstrated that the patient phase of delay was greater than the practitioner phase, whilst patient-related research suggests that recognition of symptom seriousness is more important than recognition of the presence of the symptom. The main factors related to practitioner delay were misdiagnosis, application and interpretation of tests, and the confounding effect of existing disease. Greater understanding of patient factors is required, along with evaluation of interventions to ensure appropriate diagnosis, examination and investigation.

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Section: Delay Intervalsmentioning

confidence: 99%

Section: Factors Influencing Patient Delaymentioning

confidence: 99%

Systematic review of factors influencing patient and practitioner delay in diagnosis of upper gastrointestinal cancer

et al. 2006

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“…It has been pointed out that the prognosis in young patients with a gastric cancer was no worse than that in the population as a whole, if the lesion was detected before the cancer reached the subserosa (Bedikian et al, 1979;Mori et al, 1985). The cure rate for cancer of the stomach in young adults seems to depend entirely on an early diagnosis.…”

Section: Clinicopathologicalfactorsmentioning

confidence: 99%

“…Gastric cancer is considered to be a disease of the middle aged and elderly; indeed, the peak incidence is in patients over age 50 years (Bedikian et al, 1979;Bloss et al, 1980). It has been reported that only about 1-2% of all cases of gastric cancer occur in individuals aged 30 years or younger (Tso et al, 1987;Okamoto et al, 1988;Matley et al, 1988).…”

mentioning

confidence: 99%

“…It has been reported that only about 1-2% of all cases of gastric cancer occur in individuals aged 30 years or younger (Tso et al, 1987;Okamoto et al, 1988;Matley et al, 1988). The prognosis in these young patients has shown considerable variability, with the poor prognosis attributed to a delay in the diagnosis (Matsusaka et al, 1976;Bedikian et al, 1979;Bloss et al, 1980), and to a more aggressive course of disease (Tamura & Curtiss, 1960;Tso et al, 1987). However, the published literature does not make clear whether there are differences in the prognosis between the younger and the older patients.…”

mentioning

confidence: 99%

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