Gastric Carcinoma Metastases to Extraocular Muscles

Fred, W.; Gelderen, Chr van

doi:10.1097/00004728-199305000-00035

Cited by 18 publications

(2 citation statements)

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“…In as many as 25% of choroidal metastases, multiple or bilateral tumours were present; bilaterality is much less frequent in orbital metastases 45 20 25-27 In a series reported by Tijl and colleagues, four of 34 patients had bilateral orbital metastases and all of these bilateral cases had breast carcinomas 28…”

Section: Discussionmentioning

confidence: 99%

Orbital metastases: diagnosis and course

Char¹,

Miller

Kroll

1997

British Journal of Ophthalmology

198

164

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(Br J Ophthalmol 1997;81:386-390) Orbital metastases are an infrequent aetiology of adult proptosis; approximately 3-7% of orbital biopsies have domonstrated a metastatic tumour, and this diagnosis is often unexpected.1-5 Metastatic orbital deposits are less common than uveal metastases; in several series the relative incidence was approximately one to eight. 4 6 7 In both sites, a metastatic tumour may present with ophthalmic symptons before the discovery of the primary neoplasm; this more common with lung, gastrointestinal, thyroid, and renal carcinomas.4 5 In contrast, as many as 90% of breast cancers that metastasise to ocular structures have had treatment for the primary tumour.

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Section: Discussionmentioning

confidence: 99%

Orbital metastases: diagnosis and course

Char¹,

Miller

Kroll

1997

British Journal of Ophthalmology

198

164

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“…The search methodology identified 135 articles. Of these, 43 articles were included, five articles of potential interest could not be accessed and seven articles of potential interest were published in languages other than English with no translation available …”

Section: Literature Reviewmentioning

confidence: 99%

Metastasis to the extraocular muscles: a case report, literature review and pooled data analysis

Leung

Wei

Roberts

2018

Clinical Exper Ophthalmology

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Metastasis to the extraocular muscles (EOM) is rare. The existing literature comprises only of isolated case reports therefore a summative description of these lesions is lacking. This study presents a case of bilateral rectus muscle metastasis from malignant melanoma. Furthermore a literature review and pooled data analysis is undertaken with 43 articles encompassing 77 patients and 101 eyes. Mean age was 53 years, 54% were male, 66% had unilateral involvement and 34% had bilateral involvement. The primary malignancies were melanoma (n = 17, 22%), breast (n = 15, 15%) and carcinoid (n = 11, 14%). A single muscle was involved in 56 eyes (67%) and multiple muscles in 27 eyes (33%). Lateral rectus was most commonly affected (n = 44, 53%). Presenting symptoms included restricted eye movements (n = 48, 62%), proptosis (n = 45, 58%), diplopia (n = 27, 35%) and pain (n = 18, 23%). Scattered case reports have previously made it difficult to characterise this phenomenon thus a pooled data analysis is presented.

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Evaluation and Management of Metastatic Orbital Tumors

Valenzuela

McNab

2010

Oculoplastics and Orbit

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Gastric Carcinoma Metastases to Extraocular Muscles

Cited by 18 publications

References 0 publications

Orbital metastases: diagnosis and course

Orbital metastases: diagnosis and course

Metastasis to the extraocular muscles: a case report, literature review and pooled data analysis

Evaluation and Management of Metastatic Orbital Tumors

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