Gastric Electrical Stimulation for the Treatment of Gastroparesis or Gastroparesis-Like Symptoms: A Systemic Review and Meta-Analysis

Saleem, Saad; Aziz, Muhammad; Khan, Aleena Ahmad; Williams, Mary-Jane O.; Mathur, Prateek; Tansel, Aylin; Barber, Annabel; Abell, Thomas L.

doi:10.1016/j.neurom.2022.10.048

Cited by 9 publications

(2 citation statements)

References 29 publications

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“…A 1-cm-long electrode is surgically placed 10 cm proximal to the pylorus, and the wire is connected to an implanted generator to deliver high-frequency electrical pulses to the stomach, with an amplitude of 5 mA at intervals of 72 ms [ 89 ]. A recent meta-analysis suggests that GES treatment significantly improves the frequency of vomiting, gastrointestinal symptoms, and quality of life in patients [ 90 ]. A 10-year follow-up found that patients showed significant weight gain after GES, and J-tubes of 89% of the patients could be removed [ 91 ].…”

Section: Discussionmentioning

confidence: 99%

A global bibliometric and visualized analysis of the status and trends of gastroparesis research

Li,

Gao,

Wang

et al. 2023

Eur J Med Res

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Background Gastroparesis has a substantial impact on the quality of life but has limited treatment options, which makes it a public health concern. No bibliometric studies on gastroparesis have been published thus far. Thus, this article aims to summarize and analyze research hotspots to provide a reference for clinical researchers. Materials and methods Gastroparesis-related research articles were searched in the Web of Science Core Collection (WOSCC), and relevant information was extracted after screening. A total of 1033 documents were analyzed with the bibliometric method using Microsoft Excel, Citespace, and VOSviewer. Results Overall, our search retrieved 1033 papers contributed by 966 research institutions from 53 countries. Since 1980, publications in this field have increased rapidly. United States (n = 645) and Temple University (n = 122) were the most productive country and institution, respectively. Parkman, with 96 publications, was the most prominent author. Conclusions Research hotspots in gastroparesis can be summarized into four domains: innovation in diagnostic modalities, change of oral therapeutic agents, choice of surgical interventions, and pathological mechanisms. Future research on gastroparesis should focus on the quality of life of patients, diagnostic techniques, pyloromyotomy, and transpyloric stent placement.

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Section: Discussionmentioning

confidence: 99%

A global bibliometric and visualized analysis of the status and trends of gastroparesis research

Li,

Gao,

Wang

et al. 2023

Eur J Med Res

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“…Gastric electrical stimulation (GES) is a therapeutic option that has emerged in recent years for the management of refractory gastroparesis. The use of electrical stimulation to modulate gastrointestinal motility dates back to the 1970s, but its clinical application was limited due to the technical difficulties involved in implanting the devices [ 2 ]. However, technological advances have made the implantation of GES devices a safe and effective treatment option for patients with refractory gastroparesis.…”

Section: Introductionmentioning

confidence: 99%

Gastric Electrical Stimulation for Refractory Gastroparesis: A Promising Treatment Modality for Symptom Control and Gastric Emptying

Saeed¹,

Kamran²,

Bhagwani³

et al. 2023

Cureus

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Gastroparesis is a disorder with few available treatments and delayed stomach emptying. Gastric electrical stimulation (GES) has shown promise in treating the signs and symptoms of gastroparesis as well as gastric emptying by stimulating the stomach with high-frequency electrical impulses. In this case, a 43-year-old lady with refractory gastroparesis had a GES device laparoscopically implanted. Even though GES seems promising, more study is necessary to improve patient choice, technique, and long-term results. Patients with refractory gastroparesis who have not responded to traditional therapy should be considered for GES, with treatment decisions being made individually depending on clinical presentation and patient preferences.

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European Guideline on Chronic Nausea and Vomiting—A UEG and ESNM Consensus for Clinical Management

Malagelada,

Keller,

Sifrim

et al. 2025

UEG Journal

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IntroductionChronic nausea and vomiting are symptoms of a wide range of gastrointestinal and non‐gastrointestinal conditions. Diagnosis can be challenging and requires a systematic and well‐structured approach. If the initial investigation for structural, toxic and metabolic disorders is negative, digestive motility and gut‐brain interaction disorders should be assessed. United European Gastroenterology (UEG) and the European Society for Neurogastroenterology and Motility (ESNM) identified the need for an updated, evidence‐based clinical guideline for the management of chronic nausea and vomiting.MethodsA multidisciplinary team of experts in the field, including European specialists and national societies, participated in the development of the guideline. Relevant questions were addressed through a literature review and statements were developed and voted on according to a Delphi process.ResultsNinety‐eight statements were identified and voted following the Delphi process. Overall agreement was high, although the grade of scientific evidence was low in many areas. Disagreement was more evident for some pharmacological treatment options. A diagnostic algorithm was developed, focussing on the differentiating features between gastrointestinal motility and gut‐brain interaction disorders with predominant nausea and vomiting.ConclusionThese guidelines provide an evidence‐based framework for the evaluation and treatment of patients with chronic nausea and vomiting.

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Gastric Electrical Stimulation for the Treatment of Gastroparesis or Gastroparesis-Like Symptoms: A Systemic Review and Meta-Analysis

Cited by 9 publications

References 29 publications

A global bibliometric and visualized analysis of the status and trends of gastroparesis research

A global bibliometric and visualized analysis of the status and trends of gastroparesis research

Gastric Electrical Stimulation for Refractory Gastroparesis: A Promising Treatment Modality for Symptom Control and Gastric Emptying

European Guideline on Chronic Nausea and Vomiting—A UEG and ESNM Consensus for Clinical Management

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