Gastric Embolization as Treatment for Overweight Patients; Efficacy and Safety

Elens, Stéphanie; Roger, T.; Elens, Maxime; Rommens, Jacques; Sarafidis, Alexandre; Capelluto, Elie; Delcour, Christian

doi:10.1007/s00270-018-2130-x

Cited by 29 publications

(37 citation statements)

References 14 publications

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“…[8] There has only been one case in the literature that mentioned a patient having bariatric surgery after LGA embolization. [9] However, this case has only been mentioned in the results section of the study with no clear details about the patient and the outcome of the surgery or the weight changes postoperatively. The presented patient had a successful gastric sleeve surgery 3 years after BAE procedure with no morbidity related to the prior LGA embolization.…”

Section: Discussionmentioning

confidence: 99%

Uneventful sleeve gastrectomy post bariatric arterial embolization

Ashour

Karsou

Bakhsh³

2020

The Arab Journal of Interventional Radiology

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We present the case of a 42-year-old female patient who successfully and uneventfully underwent gastric sleeve surgery 3-years after left gastric artery embolization, for the treatment of obesity. This case highlights that left gastric artery embolization may not preclude future bariatric surgeries in this subset of patients who initially fail to lose weight after bariatric arterial embolization (BAE).

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Section: Discussionmentioning

confidence: 99%

Uneventful sleeve gastrectomy post bariatric arterial embolization

Ashour

Karsou

Bakhsh³

2020

The Arab Journal of Interventional Radiology

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“…In a study by Elens et al, only one patient out of 16 participants developed a major complication, i.e. pancreatitis associated with splenic infarction and gastric perforation [24]. On the other hand, one out of 21 patients in the clinical trial by Kim et al, reported death related to the medical history of the patient [30].…”

Section: Safety Of Left Gastric Artery Embolizationmentioning

confidence: 98%

“…Upper endoscopy one to two months after the procedure in 10 participants. Preliminary clinical studies show that LGE is a safe and well-tolerated procedure [23][24][25][26][27][28], but the safety and effectiveness of the LGE procedure, if performed for a second time after a certain time period, is not established.…”

Section: Safety Of Left Gastric Artery Embolizationmentioning

confidence: 99%

Future of Bariatric Embolization: A Review of Up-to-date Clinical Trials

Aldawudi

Katwal

Jirjees

et al. 2020

Cureus

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Obesity is a significant health issue with an overall rise in mortality; it has multiple risk factors, including hormonal effects, which play a significant role in the balance of food intake and weight gain. Ghrelin is an anabolic hormone secreted from stomach fundus and plays a significant role in this regulation. Management of obesity involves multiple interventions, including lifestyle adjustment, pharmacotherapy, and bariatric surgery. Bariatric embolization is a relatively new procedure; several animal studies show that embolization of the left gastric artery reduces serum ghrelin and induces weight loss. Also, several clinical studies were conducted in the past ten years which have shown bariatric embolization's effectiveness in inducing weight loss: a meta-analysis of 47 patients included in six different clinical studies of left gastric artery embolization resulted in 8% total weight loss from baseline body weight. Many studies also show this procedure's effect on lowering the HgA1C level and lipid profile. Clinical studies mostly reported minor adverse effects such as transient abdominal discomfort, nausea and vomiting, gastric ulcers, and major adverse effects were uncommon, suggesting the procedure is well tolerated. It may be an alternative line of management in patients who are not suitable candidates for bariatric surgery. Although future clinical studies will provide an answer to several questions like the exact effects of the procedure on diabetes and metabolic syndrome, future studies are also needed to establish particular guidelines to match different patient characteristics with their optimal procedural techniques and pre-and post-procedure evaluation tests.

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“…Ghrelin is the only known orexigenic gastrointestinal hormone produced in the gastric fundus and proximal gut. Recent studies have shown that the embolization of the left gastric artery induces appetite suppression and weight loss. A possible reason is that the blockage of major blood supply to the stomach fundus inhibits its function, including the generation of ghrelin.…”

Section: Mechanisms Of Weight Lossmentioning

confidence: 99%

Mechanisms of Weight Loss After Sleeve Gastrectomy and Adjustable Gastric Banding: Far More Than Just Restriction

Wang

Guo

et al. 2019

Obesity

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Obesity has reached global epidemic proportions in recent decades. Bariatric surgery is currently accepted as most effective in alleviating morbid obesity and related disorders. Sleeve gastrectomy (SG) and adjustable gastric banding (AGB) have gained popularity since the beginning of this century because of their efficacy, safety, and simplicity. SG, in particular, has emerged as the most popular bariatric procedure because of its simpler concept and shorter operative time compared with gastric bypass. Caloric restriction, however, cannot account for the sustained weight loss and improved glucose metabolism seen following SG and AGB. Other mechanisms, including changes in gastrointestinal hormone secretion, rearrangement of hypothalamic and vagal control, alteration in energy expenditure, and re‐regulation of bile acid metabolism and the intestinal flora environment, are thought to contribute to the postoperative benefits. This review focuses on clinical and experimental literature addressing the potential mechanisms for SG and AGB procedures in human and animal models. Understanding such mechanisms can provide important insight into how current gastric restrictive procedures work and how future treatments of obesity, both surgical and nonsurgical, can be developed.

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Gastric Embolization as Treatment for Overweight Patients; Efficacy and Safety

Cited by 29 publications

References 14 publications

Uneventful sleeve gastrectomy post bariatric arterial embolization

Uneventful sleeve gastrectomy post bariatric arterial embolization

Future of Bariatric Embolization: A Review of Up-to-date Clinical Trials

Mechanisms of Weight Loss After Sleeve Gastrectomy and Adjustable Gastric Banding: Far More Than Just Restriction

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