Gastric Eosinophilic Granuloma Related to Anisakiasis Resected by Laparoscopic and Endoscopic Cooperative Surgery

Namikawa, Tsutomu; Marui, Akira; Yokota, Keiichiro; Yamaguchi, Sachi; Fukudome, Ian; Uemura, Sunao; Munekage, Masaya; Maeda, Hiromichi; Kitagawa, Hiroyuki; Kobayashi, Mariko; Hanazaki, Kazuhiro

doi:10.21873/cdp.10068

Cited by 2 publications

(1 citation statement)

References 13 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…[ 5 , 23 ]. Indeed, the chronic form of the disease can result in granulomatous tissue formation, presenting as firm masses difficult to differentiate from neoplasm (mesenchymal tumours), radiologically and macroscopically [ 3 , 4 , 16 , 26 , 27 ]. This form of the disease carries unfamiliar risks emerging serious diagnostic and therapeutic dilemmas.…”

Section: Discussionmentioning

confidence: 99%

First Case of Human Anisakiosis in Greece: Acute Invasive Infection Mimicking Peritoneal Malignancy

Dinas,

Diakou,

Vasiliadis

et al. 2024

Pathogens

View full text Add to dashboard Cite

Consumption of raw and mildly processed seafood, in the context of modern Western world eating trends, is recognized as a major driver for human fish-borne infections. However, these zoonoses and their unfamiliar risks remain neglected and underappreciated among European diagnosticians. In contemporary Europe anisakidosis is one of the most important fish-borne zoonoses. It is caused by ingesting the third-stage infective larvae of the nematode parasites that belong to the family Anisakidae. The case described herein, is an intestinal and ectopic form of anisakiosis (Anisakis spp.), causing symptoms of subacute abdomen and masquerading as an intraperitoneal malignancy. It is the first anisakidosis case reported in Greece, affecting a young patient who had been repeatedly exposed to the parasite by consuming homemade raw fish. Right hemicolectomy, omentectomy and excision of a descending colon nodule were uneventfully performed. The pathology report confirmed granulomatous tissue with eosinophilic infiltration and parasites that were morphologically and molecularly identified as Anisakis spp. Although challenging, acquiring an accurate diagnosis of anisakidosis can prevent unnecessary surgery, as the infection typically is self-resolving, and if treatment is deemed necessary, it can be limited to antiparasitic medication. However, in rare cases, extra-gastrointestinal migration of larvae can cause severe damage with practically unknown risks, posing a diagnostic and therapeutic dilemma. In such a clinical case scenario, surgical exploration can decisively contribute to a definitive diagnosis and early identification of intraabdominal complications necessitating surgical intervention.

show abstract