Gastric Fibromatosis

Abstract

Gastrointestinal fibromatosis is a rare mesenchymal tumor. It has local invasive behaviour with low-metastatic potential. We present a 36-year-old female patient presented to Oncology Center, Mansoura University, Egypt, with accidentally discovered gastric mass by abdominal computed tomography (CT). The mass was adherent to the posterior wall of the gastric fundus, the tail of pancreas and encasing the splenic artery. The patient underwent partial gastrectomy, distal pancreatectomy and splenectomy. Pathological examination of the specimen showed bland spindle cell proliferation, with oval nuclei, scanty eosinophilic cytoplasm. There was no detected mitosis or necrosis or haemorrhage. Immunohistochemistry of tumor cells was positive with β-catenin and SMA, while Desmin, CD117, DOG-1 and S-100 were negative. The patient did not receive any adjuvant therapy. The patient underwent strict periodic follow-up every 3 months with abdominal CT for 6 months after surgery.