Gastric glomus tumor presenting with massive upper GI bleeding: A challenging to diagnose and treat tumor

Ayash, Ahmad; Elkomy, Nasrein; Almohannadi, Muneera; Kaabi, Saad Rashid Al; Petkar, Mahir

doi:10.1002/ccr3.6172

Cited by 4 publications

(2 citation statements)

References 12 publications

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“…A minimally invasive intervention is desired. The most used procedures are wedge resection, subtotal gastrectomy, or tumor resection [ 21 , 22 ]. In small lesions, it is possible to opt for an excision through endoscopy, but the risks of hemorrhage and perforation must be weighed.…”

Section: Discussionmentioning

confidence: 99%

A 65-Year-Old Man Presenting to the Emergency Department with Gastric Hemorrhage Caused by a Glomus Tumor

Deacu,

Bosoteanu,

Orășanu

et al. 2023

Am J Case Rep

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Patient: Male, 65-year-old Final Diagnosis: Gastric glomus tumor Symptoms: Gastric hemorrhage Clinical Procedure: — Specialty: Pathology Objective: Rare disease Background: Glomus tumor is a benign but rapidly growing mesenchymal tumor that is a rare in the gastrointestinal tract, can be locally invasive due to its rapid growth, and can result in perforation of a viscus. We report a 65-year-old man presenting as an emergency with gastric hemorrhage and gastric glomus tumor. Case Report: A 65-year-old man came to our hospital for a life-threatening upper digestive hemorrhage. The preoperative examinations (digestive endoscopy without sampling of biopsy fragments and contrast-enhanced computer tomography) led to the presumptive diagnosis of gastrointestinal stromal tumor. Wedge resection of the gastric wall was performed. The histopathological examinations revealed a proliferation of round-oval cells of medium size with a solid disposition and in nests. This proliferation dissected the muscular tunic and caused ulceration of the gastric mucosa. Immunohistochemical tests confirmed the diagnosis of glomus tumor and excluded other diagnoses (neuroendocrine tumor or gastrointestinal stromal tumor). The postoperative evolution was favorable, and at the time of discharge, the biochemical test values normalized. Conclusions: Pathologists are faced with a challenging task due to the deceptive appearance that can be presented by such a rare tumor. Histopathological and immunohistochemical examinations are essential in achieving a precise diagnosis and assessing the biological potential of the glomus tumor. Even if it is a benign tumor, the clinical picture it causes can still be a major risk to the patient’s life. Consequently, ensuring effective case management becomes crucial, as it requires a thorough comprehension of all conditions encompassed in the differential diagnosis.

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Section: Discussionmentioning

confidence: 99%

A 65-Year-Old Man Presenting to the Emergency Department with Gastric Hemorrhage Caused by a Glomus Tumor

Deacu,

Bosoteanu,

Orășanu

et al. 2023

Am J Case Rep

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“…18 Indeed, the complete nail plate removal technique may carry additional complications, including slow nail regrowth, scar formation, and numbness in the affected finger or toe, resulting in a loss of sensory perceptions such as pain, temperature, touch, and pressure sensations. 19,20 The subungual approach, in addition to the complications mentioned earlier, has also been associated with nail bed injury, which can potentially lead to the spread of the lesion to surrounding tissues. Each treatment method for subungual GTs has its own benefits and side effects.…”

Section: F I G U R Ementioning

confidence: 99%

Modified nail folding approach: A novel strategy for the treatment of subungual glomus tumors—A case series study

Ahangar,

Akbaribazm,

Rahimi

et al. 2023

Clinical Case Reports

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Key Clinical MessageThe modified nail folding approach, a new surgical technique, has been shown to be safe and effective for the treatment of subungual glomus tumors, providing clinicians with a new treatment option for patients with this condition.AbstractGlomus tumors (GTs) are rare benign tumors that originate from the glomus body in the skin of the fingertips, toes, and nail beds. GTs are more prevalent in women than in men and can occur sporadically or as part of an inherited condition known as multiple GTs. The exact cause of GTs is unknown, but it is believed that mutations in the cells of the glomus body contribute to their development. In this study, we present the efficacy of a novel surgical technique called the modified nail folding approach for treating subungual GTs. We report a case series involving 17 patients who underwent the nail folding approach for surgical removal of subungual GTs. The primary objective of this article is to provide evidence supporting the safety and effectiveness of this technique. Additionally, we aim to introduce clinicians to a new, secure, and efficient treatment option for patients with subungual GTs.

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Gastric glomus tumor with a rare presentation: a case report and review of the literature

Thalji,

Alnajjar,

Mohammad

et al. 2024

Annals of Medicine &Amp; Surgery

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Introduction and Importance: Gastric glomus tumors (GGT) are rare soft tissue tumors of the gastrointestinal tracts (GIT). It is somewhat challenging to establish the diagnosis of GGT and differentiate it from the more common submucosal neoplasms. Case Presentation: A 34-year-old female patient presented with upper gastrointestinal bleeding. Extensive workup including endoscopic ultrasonography (EUS) revealed a well-circumscribed isoechoic mass arising from the muscularis propria. Based on fine needle biopsy (FNB) findings, with H&E stains performed only initially, the mass was considered a neuroendocrine tumor (NET). Antrectomy with Billroth II anastomosis was performed. A microscopic and immunohistochemical studies of the resected specimen showed the cells to be positive for smooth muscle actin (SMA) making GGT the final diagnosis. Clinical Discussion: Of the 116 patients included in our analysis, 56.9% (n=66) were females and age group was between 41-64 years old in 63.8% (n=74) of the patients. About 55 cases (47.4%) had abdominal or epigastric pain or discomfort, which was the most frequent clinical symptom. In immunohistochemistry, SMA staining is present in 68.1% of the cases, underscoring its diagnostic significance. Laparotomy with wedge or partial gastrectomy was employed in 46.1% of the recorded cases. Due to malignant potential, long-term follow-up and monitoring are usually recommended. Conclusion: Despite the rarity of GGT, they should be included in the differential diagnosis of gastric submucosal tumors, with immunohistochemistry studies playing a major role in the diagnosis. Furthermore, a comprehensive evaluation of the literature in the past eight years was presented in a table.

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Gastric glomus tumor presenting with massive upper GI bleeding: A challenging to diagnose and treat tumor

Cited by 4 publications

References 12 publications

A 65-Year-Old Man Presenting to the Emergency Department with Gastric Hemorrhage Caused by a Glomus Tumor

A 65-Year-Old Man Presenting to the Emergency Department with Gastric Hemorrhage Caused by a Glomus Tumor

Modified nail folding approach: A novel strategy for the treatment of subungual glomus tumors—A case series study

Gastric glomus tumor with a rare presentation: a case report and review of the literature

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