Gastric glomus tumor: report of one case and review

Gastric Glomus Tumor Presenting as a Submucosal Lesion of the Fundus: A Case Report and a Review of the Literature

“…The mean age of presentation is in the fifth decade [1,2,7]. Even if some gastric glomus tumors are found incidentally, the clinical presentation is symptomatic in most cases, consisting of ulcer-like symptoms or upper GI bleeding with or without anemia [1][2][3][4][5][6][7]. The most frequent localisation is the antrum [3], but it has been described in the gastric fundus in rare cases as reported in our case.…”

“…However, in recent reviews, men seem to be more affected than woman [3][4][5][6][7]. The mean age of presentation is in the fifth decade [1,2,7]. Even if some gastric glomus tumors are found incidentally, the clinical presentation is symptomatic in most cases, consisting of ulcer-like symptoms or upper GI bleeding with or without anemia [1][2][3][4][5][6][7].…”

“…The majority of gastric glomus tumors are benign [2][3][4][5][6][7]. The probability of malignant behavior is low [1,3,7], but some cases of malignant and metastatic tumors exist [1].…”

“…Nuclear atypia and spindle cell change are other malignancy factors [1]. However, metastatic glomus tumors with only mild nuclear atypia have been described [1][2][3] showing that this is not a valuable malignancy predictor. To date, there are no clear criteria for malignancy in gastric glomus tumors [7].…”

“…Therefore, the majority of glomus tumors are found in fingernails, hands and feet [2]. Gastric glomus tumors are rare [2]; the antrum being the most frequent location in the stomach [3].…”