Gastric glomus tumor with prominent polytypic plasmacytosis: case report and review of literature

Abstract

Glomus tumor is a rare benign mesenchymal tumor, mostly found in acral skin or superficial soft tissues, but it can occur in other locations. Glomus tumors in different locations share similar histological and immunohistochemical characteristics, although some aberrant features can be identified. We report a case of 41 year-old male with gastric glomus tumor, preoperatively diagnosed as CD117 negative gastrointestinal stromal tumor. Apart from the rare location, glomus tumor showed some other unusual features -peritumoral polytypic plasmacytosis and florid mesothelial hyperplasia. Although gastric glomus tumors are rare, they should be included in differential diagnosis of submucosal gastric tumors.