Gastric heterotopia in the proximal oesophagus (“inlet patch”): Association with adenocarcinomas arising in Barrett mucosa

Neumann, William L.; Lujan, Giovanni; Genta, Robert M.

doi:10.1016/j.dld.2011.11.008

Cited by 46 publications

(36 citation statements)

References 40 publications

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“…In the largest of these, a retrospective study which included 487 229 endoscopies, Neumann et al 30 showed that dysphagia, odynophagia, upper respiratory symptoms and globus were significantly more common in patients with CIP. Most show an increased presence of LPR symptoms,24 30 31 particularly globus sensation.…”

Section: Introductionmentioning

confidence: 99%

Cervical inlet patch: new insights into diagnosis and endoscopic therapy

Rusu

Ishaq

Wong

et al. 2017

Frontline Gastroenterol

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The cervical inlet patch is an island of heterotopic gastric mucosa, most commonly found in the proximal oesophagus. Its importance as a cause of throat symptoms has been recognised, particularly chronic globus sensation. This has led to a change in the Rome IV criteria for globus management, with emphasis on ruling out the condition. Proton pump inhibitors are often ineffective in resolving symptoms. Endoscopic studies on the use of ablative techniques, most recently radiofrequency ablation (RFA), have shown promise in reversing the CIP to mormal squamous mucosa, with subsequent symtpomatic resolution. The aim of this review is to update on the investigation and management of the CIP.

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Section: Introductionmentioning

confidence: 99%

Cervical inlet patch: new insights into diagnosis and endoscopic therapy

Rusu

Ishaq

Wong

et al. 2017

Frontline Gastroenterol

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“…Disfaji %15-39 arasında değişen oranlarda görülür. Literatürde en büyük seri 487.229 vakalık bir seri olup bu seride hastaların en sık bulgularının disfaji, odinofaji, LFR bulguları ile globus olduğu gösterilmiştir (11). Bizim çalışmamızda reflü şikayetleri hastaların %32.5'inde, reflü dışında disfaji şikayeti hastaların %19.7'sinde saptanmış olup reflü ve disfaji semptomları toplamda hastaların yarısın-da görülmüştür.…”

Section: Discussionunclassified

Heterotopik gastrik mukozanın sıklığı, klinik önemi ve eşlik eden diğer klinik bulgular

Savas¹,

Akbaş²

2015

Endoskopi Gastrointestinal

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“…This was sustained for a median of 17 months. Neumann et al demonstrated that although still uncommon (incidence 1.6%), presence of an inlet patch in patients with globus was more common than in those without globus symptoms (OR 5.4, 95% CI 3.17 to 9.17) in a dataset of almost half a million endoscopies 44. Other studies of ablation of cervical inlet patches in globus are uncontrolled or retrospective or report small sample sizes 45 46.…”

Section: Managementmentioning

confidence: 99%

Managing a patient with globus pharyngeus

Harvey

Theron

Trudgill

2017

Frontline Gastroenterol

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A woman aged 47 years reported the feeling of a lump in her throat for the past year. The sensation was present intermittently and usually improved when she ate. She noted it was worse with dry swallows when she felt like a tablet was stuck in her throat. The sensation had become more persistent in recent weeks leading her to worry that she had cancer. She had no cough, sore throat or hoarseness. There were no precipitating factors and no symptoms of weight loss, dysphagia, odynophagia or change in her voice. She had smoked previously and rarely had heartburn. She had no other anxieties and was not under any unusual stress. She was initially assessed by an ear, nose and throat surgeon, who found no abnormalities on examination of her neck, throat and oral cavity. Nasolaryngoscopy was normal. An upper gastrointestinal endoscopy was organised and reported a hiatus hernia, but a 3-month trial of a proton pump inhibitor did not have any impact on her symptoms. The benign nature of her symptoms was discussed at her gastroenterology follow-up appointment. She was discharged back to primary care with a final diagnosis of 'globus'. A trial of speech therapy, cognitive behavioural therapy or amitriptyline would be recommended if her symptoms became more troublesome in future.

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Gastric heterotopia in the proximal oesophagus (“inlet patch”): Association with adenocarcinomas arising in Barrett mucosa

Cited by 46 publications

References 40 publications

Cervical inlet patch: new insights into diagnosis and endoscopic therapy

Cervical inlet patch: new insights into diagnosis and endoscopic therapy

Heterotopik gastrik mukozanın sıklığı, klinik önemi ve eşlik eden diğer klinik bulgular

Managing a patient with globus pharyngeus

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