Gastric juvenile polyposis syndrome with inflammatory changes in the intervening mucosa

Abstract

Juvenile polyposis syndrome (JPS) is an autosomal dominant inherited disorder characterized by multiple hamartomatous polyps in the gastrointestinal tract, and is caused by germline mutations in SMAD4 or BMPR1A. 1 However, no pathogenic variant is found in 40% of cases, and one‐fourth of cases occur without a family history. Multiple polyps are typically found in the colon (98%), stomach (14%), duodenum (7%), jejunum, and ileum (7%).This article is protected by copyright. All rights reserved.