Gastric Myeloid Sarcoma

Abstract

Most gastric cancers are adenocarcinomas, but other malignancies can arise in the stomach. Patients with leukemia may develop myeloid sarcoma (MS) in the gastrointestinal tract. Our patient was a 68-year-old woman who was initially diagnosed with acute myeloid leukemia and underwent a matched unrelated stem cell transplantation. She was in remission for 10 years before developing a rare case of gastric MS without acute myeloid leukemia. She had partial response to chemotherapy but ultimately died because of infection. Gastric MS has an incidence of less than 1%. Gastrointestinal involvement usually involves the small intestine and rarely the stomach.

Gastric myeloid sarcoma mimicking pseudoachalasia in non-leukemic context - a singular case report

“…In cases associated with leukaemia, the diagnosis is typically straightforward. However, isolated occurrences of MS pose diagnostic challenges, particularly considering the diverse anatomical sites in which this neoplasm can develop, alongside varying clinical presentations 4 .…”