Gastritis Cystica Profunda: A Rare Tumor Mimicking Malignancy

Machicado, Jorge D.; Thosani, Nirav; Quesada, Andres; Shroff, Jennifer; Mehta, Sandhya; Spinn, Matthew; Jelinek, Katherine; Scott, L. Stuart

doi:10.14309/00000434-201210001-00702

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“…Additionally, inflammatory cell deposition or intracapsular hemorrhage may be the reason for the hyper-attenuation of cystic fluid [ 29 ]. Multiple cysts and the separation of cystic lesion have been mentioned in previous researches of GCP [ 25 , 30 – 32 ]. Similarly, this feature was observed in a few larger masses in our series.…”

Section: Discussionmentioning

confidence: 99%

Computed tomography features and clinical characteristics of gastritis cystica profunda

Wang

Liang

et al. 2022

Insights Imaging

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Background The diagnostic evidence of gastritis cystica profunda (GCP) are not adequately described due to its extremely low morbidity. This study aimed to analyze and summarize the comprehensive CT features and clinical characteristics of patients with GCP. Results Nineteen patients were enrolled, including eight men and eleven women, with a mean age of 55.53 years. Only one patient had the history of gastric polypectomy. Among the nineteen cases, two cases were in the gastric cardia, four in the gastric fundus, eight in the gastric body and five in the gastric antrum. The shapes were sphere in thirteen patients, hemisphere in five patients and diffuse in one patient. The mean size of eighteen local lesions was 1.63 cm. The cystic changes in submucosa were detected in fifteen patients. Compared with the pancreas, most GCP lesions were hypo-attenuated on unenhanced CT (n = 8), in arterial phase (AP) (n = 17) and venous phase (VP) (n = 11). Fifteen patients had the peak enhancement in VP and two in AP. The rim-like enhancement with central low attenuation was clearly observed in thirteen patients. For the GCP accompanied by adenocarcinoma, the enhancement peak was present in AP and the gradual expansion of enhancement area was in VP. All patients underwent surgical or endoscopic resection. Sixteen cases had remission of symptoms and no recurrence. Conclusions The careful analysis of CT features and clinical characteristics can provide support for deepening the understanding of the GCP. However, a more accurate diagnosis depends on histopathological features.

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