Gastroentéropathies exsudatives

Dray, X.; Vahedi, K.; Rousseau, S.; Lavergne-Slove, A.; Boudiaf, M.; Marteau, P.

doi:10.1016/s1155-1968(06)43281-8

Cited by 2 publications

(3 citation statements)

References 27 publications

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“…Protein exudation can be caused by two distinct mechanisms: the first one is an increase in the permeability of the intestinal barrier, either by loss of mucosal substance with macroscopic ulcerations, resulting in leakage into the lumen of a predominantly inflammatory protein exudate, or by mucosal lesions without macroscopic ulcerations leading to a leakage of plasma proteins, while the second mechanism is increasing hydrostatic pressure in the interstitium leading to a leakage of lymph. Therefore, the greater the exudation, the greater the plasma loss [3,4].…”

Section: Discussionmentioning

confidence: 99%

Exudative enteropathy in neonates: A case report

Zizi¹,

Elouardighi²,

Amalik³

et al. 2023

World J. Bio. Pharm. Health Sci.

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The term exudative gastroenteropathy is used to describe an entity characterized by excessive loss of plasma proteins in the gastrointestinal tract. This digestive exudation can be caused either by an obstacle to intestinal lymphatic drainage or by an alteration of the epithelial barrier. The clinical picture is often associated with chronic diarrhea and an edematous syndrome. Lymphedema, infectious complications secondary to lymphopenia or hypogammaglobulinemia, and thromboembolic complications may also be observed. Diagnosis is based on the measurement of fecal alpha-1 antitrypsin clearance. Sometimes primary in the context of Waldmann disease (primary intestinal lymphangiectasis) but more often secondary. It requires an endoscopic and morphological workup to confirm the origin of the protein leak, to evaluate its extent and cause. In addition to etiological treatment, management is based on a hyperprotein and hypolipid diet with medium-chain triglyceride supplementation. We report the case of an exudative enteropathy in a newborn.

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Section: Discussionmentioning

confidence: 99%

Exudative enteropathy in neonates: A case report

Zizi¹,

Elouardighi²,

Amalik³

et al. 2023

World J. Bio. Pharm. Health Sci.

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“…L'adjonction des triglycéri-des à chaînes moyennes et un enrichissement en protides et en vitamines liposolubles permettent d'apporter les besoins organiques indispensables [7].…”

Section: Discussionunclassified

“…En cas d'échec, on peut avoir recours à la nutrition parentérale exclusive [7], à l'octréotide (200 mg Â 2/j) ou les antiplasmines dont l'efficacité est inconstante [8]. Dans les formes limitées de la maladie, une résection chirurgicale peut être indiquée avec une évolution favorable [6].…”

Section: Discussionunclassified

Maladie de Waldmann. À propos de deux observations

Tlemsani

Khannousi

Kabbaj

et al. 2008

J Afr Hepato Gastroenterol

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La maladie de Waldmann (lymphangiectasies intestinales primitives) est responsable d'une entéropathie exsudative par fuite de la lymphe dans la lumière digestive.Nous rapportons deux observations de patients qui présentaient un syndrome oedémateux avec une hypoprotidémie et une lymphopénie dues à une entéropathie exsudative. Les investigations morphologiques et histologiques permettaient le diagnostic de la maladie de Waldmann. Le régime diététique à base de triglycérides à chaîne moyenne était partiellement efficace. L'évolution était marquée par la survenue d'un mal de Pott cervical chez un patient et par le décès de l'autre patient.Abstract: Primary intestinal lymphangiectasia leads to a protein-losing enteropathy due to lymph leak into the intestinal tract. We report observations of two patients who presented oedema, hypoproteinemia and lymphopenia due to protein-losing enteropathy. Radiological, endoscopic and histological investigations revealed primary intestinal lymphangiectasia. Dietary treatment with middle chain triglycerides was partially effective. One patient developed tuberculous spondylodiscitis of the cervical discs and the other patient died.

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Gastroentéropathies exsudatives

Cited by 2 publications

References 27 publications

Exudative enteropathy in neonates: A case report

Exudative enteropathy in neonates: A case report

Maladie de Waldmann. À propos de deux observations

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