Gastroesophageal reflux after Roux-en-Y gastric bypass: Is it just related to technical details?

Sánchez-Pernaute, Andrés; Pérez-Aguirre, Elia

doi:10.1016/j.cireng.2023.11.002

Cited by 1 publication

(1 citation statement)

References 36 publications

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“…Among them, GERD has great importance as it strongly affects quality of life (12,36) and incurs costs related to long-term use of medications, with potential sideeffects (37) and the need for additional revisional surgeries (38). Recent reports have demonstrated that among gastric bypasses, OAGB may be associated not only with biliary reflux but also with acid reflux (39), and RYGB, even if it is the gold standard procedure to treat associated obesity and GERD, is associated with a non-negligible rate of long-term reflux (12,16,(40)(41)(42).…”

Section: Discussionmentioning

confidence: 99%

Analysis of Factors Related to Gastroesophageal Reflux After Gastric Bypass at 10-Year Follow-up: A Retrospective Single-institutional Study

PETRUCCIANI,

BENOIS,

AURELLO

et al. 2024

In Vivo

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Background/Aim: Long-term gastroesophageal reflux (GERD) after gastric bypass for obesity is underestimated. The present study aimed to evaluate the rate of treated GERD and the factors influencing it in a cohort of patients who underwent gastric bypass. Patients and Methods: Patients who underwent one-anastomosis gastric bypass (OAGB) or Roux-en-Y gastric bypass (RYGB) as a primary bariatric procedure between 2010 and 2011 at a French private referral center were included in the study. The primary endpoint was the 10-year prevalence of GERD. Results: In total, 422 patients underwent RYGB and 334 underwent OAGB with a biliopancreatic limb of 150 cm. The mean age was 38.9±11.3 years, and 81.6% of patients were female; the mean preoperative body mass index was 42.8±5 kg/m 2 . Preoperative GERD was diagnosed in 40.8% of patients in the total cohort, 31.7% in the RYGB group versus 49.1% in the OAGB group (p<0.0001). At 10-year followup, the rate of GERD was 21.1%, with no difference between the two groups. Remission of preoperative GERD and de novo GERD were comparable between the two types of bypass. Surgery for GERD resistant to medical treatment was more frequent in the OAGB group. At multivariate analysis, factors significantly correlated with long-term GERD were: Preoperative GERD, total weight loss at 120 months <25%, glycemic imbalances and anastomotic ulcers. Conclusion: Identification and correction of modifiable factors may help reduce the incidence of long-term GERD.

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