Gastroesophageal reflux disease and oral manifestations

Romano, Claudio; Cardile, Sabrina

doi:10.1186/1824-7288-40-s1-a73

Cited by 8 publications

(6 citation statements)

References 6 publications

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“…Oral soft tissue can be damaged by GERD, too [56]. Association with GERD has been proposed for tonsillitis, mucosal atrophy, erythema of the soft palate and uvula, glossitis, epithelial atrophy, xerostomia, and dysgeusia [63]. Common oral cavity complaints in GERD patients are oral dryness, acid and bitter taste, halitosis, itching and burning, and pharyngeal discomfort [56].…”

Section: Oral Soft Tissue Disordersmentioning

confidence: 99%

Extra-Esophageal Presentation of Gastroesophageal Reflux Disease: 2020 Update

Durazzo

Lupi

Cicerchia

et al. 2020

JCM

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Gastroesophageal reflux disease (GERD) is defined by the presence of symptoms induced by the reflux of the stomach contents into the esophagus. Although clinical manifestations of GERD typically involve the esophagus, extra-esophageal manifestations are widespread and less known. In this review, we discuss extra-esophageal manifestations of GERD, focusing on clinical presentations, diagnosis, and treatment. Common extra-esophageal manifestations of GERD include chronic cough, asthma, laryngitis, dental erosions, and gingivitis. Extra-esophageal involvement can be present also when classic GERD symptoms are absent, making the diagnosis more challenging. Although available clinical studies are heterogeneous and frequently of low quality, a trial with proton pump inhibitors can be suggested as a first-line diagnostic strategy in case of suspected extra-esophageal manifestations of GERD.

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Section: Oral Soft Tissue Disordersmentioning

confidence: 99%

Extra-Esophageal Presentation of Gastroesophageal Reflux Disease: 2020 Update

Durazzo

Lupi

Cicerchia

et al. 2020

JCM

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“…Also, there are extraesophageal symptoms related to acid reflux such as chronic cough and dental erosion, while complications vary from esophagitis to Barrett's esophagus and esophageal adenocarcinoma [1]. Many studies documented oral symptoms of GERD that can be include dental caries, dry mouth, feeling of acid/burning sensation, halitosis, erythema of the oral mucosa especially palatal mucosa, and uvula [4]. Another study demonstrates microscopic changes in the palatal mucosa of GERD patients represented by mucosal atrophy and increase in fibroblast [5].…”

Section: Introductionmentioning

confidence: 99%

Untitled

2023

J. Med. Chem. Sci.

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The neutralization of stomach's acidic contents and protection of esophageal mucous membrane during reflux episodes is the primary function of the major buffering components of saliva, bicarbonate, and phosphate. The concentrations of inorganic compounds in the saliva of subjects who have Gastroesophageal reflux disease versus healthy individuals are poorly understood. In this work, the aim of study was to assess the occurrence of soft tissues alterations and symptoms in oral cavity and analysis of bicarbonate and phosphate to evaluate their levels in saliva of patients with GERD and compare with control individuals. A case-control study included 25 GERD patients diagnosed both clinically and endoscopically (GERD Group), 25 patients with upper gastrointestinal symptoms with no endoscopic signs of GERD (non GERD group) and 25 healthy subjects (control group) have been evaluated through visual examination of the oral mucosa, oral symptoms, nonstimulated salivary flow rate, swallowing function, in addition to the estimation of salivary concentration of bicarbonate and phosphate. Study result was significantly higher salivary bicarbonate in GERD patients (p<0.05), significantly lower Salivary flow rate and swallowing frequency compared to non-GERD group and control group. Among the patients with GERD, 56% of the cases suffering from oral dryness, 40% halitosis, 28% acid taste, 20% burning sensation, 20% palatal erythema. Salivary bicarbonate, oral symptom and mucosal alteration were shown to be significantly related to GERD. Therefore, GERD should be taken into account by dentists as a possible risk factor for oral health K E Y W O R D S Gastroesophageal reflux disease Oral symptoms Salivary flow rate Salivary bicarbonate Salivary phosphate

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“…4 Oral manifestations of GERD include dental erosion, dental caries, xerostomia, burning sensation, halitosis, and erythema of the palatal mucosa and uvula. 5 Ulcerative colitis is a type of inflammatory bowel disease that primarily affects the colonic mucosa. Initial symptoms include diarrhea with blood and mucus, fever, and weight loss.…”

Section: Introductionmentioning

confidence: 99%

A Clinicopathologic Study of Oral Changes in Gastroesophageal Reflux Disease, Gastritis, and Ulcerative Colitis

Vinesh¹,

Masthan

Ms³

et al. 2016

The Journal of Contemporary Dental Practice

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Objectives The aim and objectives of this study are to identify oral changes in certain gastrointestinal (GI) diseases, namely gastroesophageal reflux disease (GERD), ulcerative colitis, gastritis, and to evaluate these oral symptoms as indicators for assessing GI disorders. Materials and methods In this study, the oral manifestations of various GI disorders were assessed in a varying age group of 250 patients in Government Stanley Medical College and Hospital, Chennai. Out of 250 patients, 142 were affected by GERD, 99 were affected by gastritis, and 9 patients were affected by ulcerative colitis. Of these patients, 177 were males and 73 were females. Results Evaluation of patients with gastritis revealed that 66.7% affected with gingivitis, 19.2% with dental erosion on the palatal and lingual aspects of maxillary and mandibular teeth predominantly in the anterior region, 10.1% with periodontitis, 2% with gingival erythema. Among the patients with GERD, 44% of the cases showed dental erosion, 25.5% periodontitis, 9.9% gingivitis, 5.7% gingival erythema, 2.8% palatal erythema, 2.1% gingival ulcers, glossitis 2%, 1.4% floor of the mouth erythema, and 0.7% erythema of the tongue. Patients with ulcerative colitis showed 44.4% of gingival erythema, 33.3% of dental erosions, and 22.2% of gingival ulcers and periodontitis. Conclusion In our study of 250 patients, oral manifestations were observed in 88% of the patients. Both soft tissue and hard tissue changes were evident. There was a high correlation between various GI disease and dental erosion, erythema at various sites of the oral cavity, oral ulcers, gingivitis, periodontitis, and glossitis. Careful evaluation of oral cavity may unveil many GI disorders and help the patient by providing early diagnosis, which further facilitates the prognosis. How to cite this article Vinesh E, Masthan KMK, Kumar MS, Jeyapriya SM, Babu A, Thinakaran M. A Clinicopathologic Study of Oral Changes in Gastroesophageal Reflux Disease, Gastritis, and Ulcerative Colitis. J Contemp Dent Pract 2016;17(11):943-947.

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Gastroesophageal reflux disease and oral manifestations

Cited by 8 publications

References 6 publications

Extra-Esophageal Presentation of Gastroesophageal Reflux Disease: 2020 Update

Extra-Esophageal Presentation of Gastroesophageal Reflux Disease: 2020 Update

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A Clinicopathologic Study of Oral Changes in Gastroesophageal Reflux Disease, Gastritis, and Ulcerative Colitis

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