2015
DOI: 10.5812/ircmj.15001
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Gastrointestinal Complications of Ferrous Sulfate in Pregnant Women: A Randomized Double-Blind Placebo-Controlled Trial

Abstract: Background:Some pregnant women discontinue iron supplements consumption due to Gastrointestinal (GI) complications, whereas pregnancy induces the same complications physiologically.Objectives:The aim of the present study was to assess GI complications of ferrous sulfate in pregnant women.Patients and Methods:This randomized, double-blind, placebo-controlled clinical trial was performed on 176 pregnant women referred to prenatal care clinic of Maryam Hospital from April 2011 to February 2012. Pregnant women wit… Show more

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Cited by 10 publications
(6 citation statements)
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“…Four papers reported on GI side effects 27,29,39,40 . These included nausea, vomiting, constipation, diarrhoea, abdominal pain, loss of appetite and heartburn.…”
Section: Resultsmentioning
confidence: 99%
“…Four papers reported on GI side effects 27,29,39,40 . These included nausea, vomiting, constipation, diarrhoea, abdominal pain, loss of appetite and heartburn.…”
Section: Resultsmentioning
confidence: 99%
“…A search strategy was prepared and launched in Medline and the Cochrane Library covering the period between February 2015 to February 2018 to update the evidence retrieved from the systematic reviews. The title and abstract of 230 records were screened and after 10 full‐texts were examined, two trials remained for inclusion . Jafarbegloo (2015) evaluated the gastrointestinal complications of ferrous sulfate in pregnant women whereas Zhao (2015) evaluated the effect of prenatal iron supplementation on maternal anemia, iron deficiency, and iron deficiency anemia.…”
Section: Resultsmentioning
confidence: 99%
“…The title and abstract of 230 records were screened and after 10 full‐texts were examined, two trials remained for inclusion . Jafarbegloo (2015) evaluated the gastrointestinal complications of ferrous sulfate in pregnant women whereas Zhao (2015) evaluated the effect of prenatal iron supplementation on maternal anemia, iron deficiency, and iron deficiency anemia. This update raised the number of our primary studies to 29 (Figure ).…”
Section: Resultsmentioning
confidence: 99%
“…Five publications included pregnant women as study participants. In four of the studies, ferrous sulfate (Etheredge et al 2015;Jafarbegloo et al 2015;Chan et al 2009;Makrides et al 2003) and in one study, ferrous fumarate (Darwish et al 2019) was used as compounds for the intervention. The doses of iron applied were in the range between 20 (Makrides et al 2003) and 180 mg/day (Darwish et al 2019).…”
Section: Adverse Gastrointestinal Effects In Pregnant Femalesmentioning
confidence: 99%