Gastrointestinal: Hepatic abscess after botulinum toxin type—A therapy for achalasia

Giles, Henry; Ross, Alison; Gearry, Richard B.

doi:10.1111/jgh.13719

Cited by 3 publications

(2 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…By inference, we can estimate that some of these complications can also be seen for EO and policanol injection (Grade: D). The severe complications related to BTX included hepatic (38) or subphrenic abscess (39), esophageal perforation, mediastinitis, and thoracic aorta pseudoaneurysm (40-42) (Level 4; Grade: C). The use of echoguided injection can be considered to avoid severe complications, although there is no clear evidence of the superiority of the echoguided over blinded injection regarding safety (Level 2b; Grade: B) (43).…”

Section: Botulinum Toxin Injectionmentioning

confidence: 99%

Evaluating the Non-conventional Achalasia Treatment Modalities

Tustumi

2022

Front. Med.

View full text Add to dashboard Cite

IntroductionAchalasia is a primary esophageal dysmotility disorder. Despite the high volume of studies addressing the conventional treatments for achalasia, few are debated regarding the non-conventional treatments, such as cardiectomy, cardioplasty, endoluminal substances injection (ethanolamine oleate, polidocanol, botulinum toxin), stents, and certain drugs (beta-agonists, anticholinergic, nitrates, calcium channel blockers, and phosphodiesterase inhibitors).MethodsA critical review was performed.ResultsEndoscopic, surgical, and pharmacological treatments were included. A qualitative synthesis was presented.ConclusionNon-conventional therapeutic options for treating achalasia encompass medical, endoscopic, and surgical procedures. Clinicians and patients need to know all the tools for the management of achalasia. However, several currently available studies of non-conventional treatments lack high-quality evidence, and future randomized trials are still needed.

show abstract

Section: Botulinum Toxin Injectionmentioning

confidence: 99%

Evaluating the Non-conventional Achalasia Treatment Modalities

Tustumi

2022

Front. Med.

View full text Add to dashboard Cite

show abstract

“…7 Case reports of subdiaphragmatic abscess, hepatic abscess, and respiratory failure from paralysis have also been published. [8][9][10] The risk of botox therapy is essentially considered the risk of sedation for an endoscopy.…”

Section: Technique and Safetymentioning

confidence: 99%

The Limited Role for Botox in Achalasia: A Gastroenterologist’s Perspective

Jodorkovsky

2022

Foregut: The Journal of the American Foregut Society

View full text Add to dashboard Cite

Botox injection during endoscopy is highly effective in patients with achalasia. However, treatment response is short in duration which poses a challenge in this chronic disease. There is limited data to suggest botox increases subsequent procedure technical difficulty or adverse events, and short term efficacy appears to be equal to other therapies. Therefore, botox is an appropriate therapy for those who require a bridge, like pregnant patients, or in high risk patients who are not candidates for myotomy. However, long term outcomes of treatment naïve patients undergoing definitive therapy may be better than previously treated patients, therefore, avoidance of botox is recommended when definitive therapy is possible. When the diagnosis of achalasia is in question, or if the presentation is not clear, botox could elucidate the treatment plan without major consequence on future therapies.

show abstract

Botulinum toxin-A

2017

Reactions Weekly

View full text Add to dashboard Cite

Gastrointestinal: Hepatic abscess after botulinum toxin type—A therapy for achalasia

Cited by 3 publications

References 0 publications

Evaluating the Non-conventional Achalasia Treatment Modalities

Evaluating the Non-conventional Achalasia Treatment Modalities

The Limited Role for Botox in Achalasia: A Gastroenterologist’s Perspective

Botulinum toxin-A

Contact Info

Product

Resources

About