Gastrointestinal Mucormycosis Mimicking Necrotizing Enterocolitis of Newborn

Raveenthiran, V

doi:10.47338/jns.v2.53

Cited by 2 publications

References 24 publications

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Gastrointestinal Mucormycosis of Neonate Masquerading as Necrotising Enterocolitis

Muthukanagarajan¹,

Karnan²,

Sadagopan³

et al. 2016

jemds

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Mucormycosis is a rare opportunistic invasive fungal infection that seldom infects healthy persons. Mucormycosis can affect any organ in the body among which gastrointestinal mucormycosis is very rare. Antemortem or preoperative diagnosis of gastrointestinal mucormycosis is not possible until histopathological demonstration of the fungal elements is done. Treatment consists of surgical debridement with systemic antifungal therapy with amphotericin B. The high mortality rate associated with GIMN (Gastrointestinal Mucormycosis of Neonate) is not only due to delay in diagnosis, but also because of inadequate and inappropriate treatment. All the infants with bowel surgery done for perforating or inflammatory lesions should be subjected to careful histopathological examination, else atypical causes for bowel perforations like GIM might be missed. Herewith presenting a rare case of gastrointestinal mucormycosis that occurred in a full-term, 5-day-old immunocompetent neonate.

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Gastrointestinal Mucormycosis of Neonate Masquerading as Necrotising Enterocolitis

Muthukanagarajan¹,

Karnan²,

Sadagopan³

et al. 2016

jemds

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Cytological Diagnosis of Infectious Diseases: Identification of Pathogens and Recognition of Cellular Reactions

Tsutsumi¹

2021

Innate Immunity in Health and Disease

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Cytological diagnosis of infectious diseases is as important as the cytodiagnosis of malignancies, because the detection of pathogens in cytological specimens is crucially valuable for prompt and appropriate patients’ treatment. When compared with histological diagnosis, cytology is strong at detecting microbes under Papanicolaou and Giemsa stains. Host response against the infectious agent can be estimated by the type of background inflammatory cells. Patterns of the inflammatory cellular responses against extracellular and intracellular pathogens should be recognized. Immunocytochemical and molecular approaches can be applied, even when we have only one cytology specimen in hand. The cell transfer technique is useful to create plural material from one glass slide for immunocytochemistry and other techniques. In case of transmissible disorders including sexually transmitted diseases, the prompt and appropriate diagnosis will avoid avoidable transmission of infectious agents among people, and eventually contribute to the safety of the human society.

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Gastrointestinal Mucormycosis Mimicking Necrotizing Enterocolitis of Newborn

Abstract: Please see fulltext

Cited by 2 publications

References 24 publications

Gastrointestinal Mucormycosis of Neonate Masquerading as Necrotising Enterocolitis

Gastrointestinal Mucormycosis of Neonate Masquerading as Necrotising Enterocolitis

Cytological Diagnosis of Infectious Diseases: Identification of Pathogens and Recognition of Cellular Reactions

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