Gastrointestinal Nerves, Hormones and Autacoids in Relation to Human Gastrointestinal Motility

Bennett, A. B.

doi:10.1007/978-1-4684-4853-5_6

Cited by 2 publications

(1 citation statement)

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“…Motilin is a peptide that does not belong to either the CCK or secretin families of hormones. Motilin regulates gut motility and in the oesophagus, stomach, small intestine and colon, the effects of motilin are opposite to the effects of CCK (Bennett, 1983). In the worm's habitat in the bile duct, the sphincter of Oddi regulates bile flow into the duodenum ; CCK relaxes the muscle to allow bile flow, while motilin contracts this muscle to prevent bile flow (Hogan, Dodds & Geenen, 1983;Wood & Jenkins, 1983).…”

Section: Discussionmentioning

confidence: 99%

Gastrointestinal hormones: environmental cues for Fasciola hepatica?

Sukhdeo

1989

Parasitology

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The effects of pharmacological concentrations of several gastrointestinal hormones on the rate of sucker activity and the frequency and the amplitude of spontaneous longitudinal muscle contractions have been examined in adult Fasciola hepatica. Caerulein and serum decrease the rate of oral sucker activity; motilin decreases and CCK-PZ increases ventral sucker activity when compared to controls. Caerulein, serum and motilin significantly inhibit the frequency of contractions while bile, caerulein and motilin decrease the amplitude of contractions. These results suggest that F. hepatica can recognize and respond to certain gastrointestinal hormones and there may be adaptive value in these behavioural responses.

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Section: Discussionmentioning

confidence: 99%