Gastrointestinal spectrum of dengue fever in a dengue epidemic

Tiwary, Indrajeet Kumar

doi:10.7869/tg.354

Cited by 2 publications

(2 citation statements)

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“…In a study 8.6% of patients with Dengue fever had acute cholecystitis, 8.6% acute viral hepatitis, 5.7% had acute appendicitis, 5.7% had acute pancreatitis. 9 Of these GI manifestations nausea, vomiting, pain abdomen, GI bleed, jaundice, ascites, elevation of transaminases, acute fulminant hepatitis and acute pancreatitis correlated with severity of Dengue fever. In a study by Pain abdomen, abdominal tenderness, ascites, hepatomegaly and jaundice were predictors of need for Intensive care.…”

Section: Discussionmentioning

confidence: 96%

Study of gastrointestinal manifestations in Dengue fever

Prashanth

Manasa

2019

Int J Adv Med

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Background: Dengue is an arthropod borne viral haemorrhagic fever. In India between 2015-2017, 790 deaths have been recorded according to NVBDCP data. Gastrointestinal manifestations are among the most common manifestations in dengue fever, and are most often missed due to lack of awareness. This study aims to find the spectrum of Gastrointestinal manifestations and correlation of GI manifestations with severity of Dengue.Methods: A cross-sectional observational study was conducted on 100 consecutive cases of serologically confirmed Dengue fever. Patients were examined clinically, and laboratory data was assessed till they got discharged. Gastrointestinal manifestations of dengue fever were noted and analyzed.Results: This study included 100 consecutive cases of dengue fever. Mean age of the study population was 32.48+12.40 years of them 77 were males and 23 were female patients. Gastrointestinal manifestations were noted in 96% of the patients. GI manifestations noted were Nausea in 71%, Elevation of transaminases in 59%, vomiting in 54%, pain abdomen in 31%, Ascites in 24% hepatomegaly in 14%, diarrhoea in 13%, Acalculous cholecystitis in 13%, Acute fulminant hepatitis in 6%, Upper GI bleed in 6%, splenomegaly in 5%, and Acute pancreatitis in 4% of patients. Of these, GI manifestations like nausea, vomiting, pain abdomen, GI bleed, ascites, jaundice, elevation of transaminases, acute fulminant hepatitis and acute pancreatitis correlated with severity of Dengue fever . Conclusion: Gastrointestinal manifestations in Dengue fever are much more common than once thought of. In our study it was found in 96 percent of patients making it most common manifestations in dengue fever. Transaminitis and Atypical GI manifestations like acute pancreatitis, acute fulminant hepatitis may indicate severe Dengue. The differential diagnosis of an acute febrile syndrome with abdominal pain or gastrointestinal symptoms in patients living in endemic areas should include Dengue fever.

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Section: Discussionmentioning

confidence: 96%

Study of gastrointestinal manifestations in Dengue fever

Prashanth

Manasa

2019

Int J Adv Med

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“…Dengue, a challenging arboviral disease 1 prevalent in the tropics, is very rarely known to present with acute colitis, with our literature search showing only two such cases 2 , 3 reported worldwide so far. Although upper gastrointestinal involvement in dengue fever is reported more frequently, including upper GI bleeding with endoscopic evidence of the same, 4 , 5 colonic involvement and colonoscopy-proven colitis are very rare. Here, we describe the case of a patient with dengue fever who presented with acute colitis and hematochezia and was treated by our department.…”

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confidence: 99%