Gastrointestinal Tract Obstruction in the Fetus

Langer, Jacob C.; Adzick, N. Scott; Filly, Roy A.; Golbus, Mitchell S.; deLorimier, Alfred A.; Harrison, Michael R.

doi:10.1001/archsurg.1989.01410100085014

Cited by 18 publications

(18 citation statements)

References 29 publications

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“…The etiology of bowel perforation includes volvulus, intussusception, atresia, Meckel's diverticulum or cystic fibrosis [4,9,12,20]. Recently, congenital infection with rubella and parvovirus B19 has been reported [21,22].…”

Section: Discussionmentioning

confidence: 99%

Correlation of Prenatal Ultrasound and Postnatal Outcome in Meconium Peritonitis

et al. 2003

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Objectives: To study the relationship between prenatal ultrasound features and postnatal course of meconium peritonitis. Methods: Meconium peritonitis was diagnosed by prenatal ultrasound. Fetuses were treated by intrauterine paracentesis of ascites when indicated, and symptomatic newborns received surgery. Results: Totally 17 cases were enrolled. Prenatal ultrasound findings include abdominal calcification (16/17), fetal ascites (12/17), hydramnios (9/17), pseudocyst (7/17) and dilated bowel loop (6/17). Persistent ascites, pseudocyst or dilated bowel loop are most sensitive (92%) to predict postnatal surgery (p = 0.022). The survivors have a higher gestational age at birth (36.4 vs. 33.3 weeks, p = 0.008). Persistent ascites and postnatal persistent pulmonary hypertension of the newborns significantly correlate with neonatal mortality (p = 0.029 and 0.022). Conclusion: Prenatal ultrasound can predict the neonatal outcome in meconium peritonitis.

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Section: Discussionmentioning

confidence: 99%

Correlation of Prenatal Ultrasound and Postnatal Outcome in Meconium Peritonitis

et al. 2003

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“…Intrauterine CMV infection has been re ported in association with both hepatic and nonhepatic fetal intra-abdominal calcifica tions [9], Often these fetuses may have coexis tent ascites or pericardial or pleural effusions [12,13], In the present study, several fetuses had the ultrasound appearance of scattered intra-abodminal calcifications, although none was shown to have a clinically significant CMV infection afterbirth.…”

Section: Discussionmentioning

confidence: 51%

“…These authors followed 6 fetuses confirmed at birth to have distal bowel obstruction. Three had polyhydramnios, 1 had confirmed cystic Fibrosis, and 1 was being observed as an infant for an indeterminate sweat chloride test [9]. The latter 2 fetuses had intra-abdominal calcifications and ascites.…”

Section: Discussionmentioning

confidence: 99%

“…Caspi et al [1] described enlarged bowel loops within an echogenic mass as consistent with these entities. Langer et al [9] reported that the sonographic findings most diagnostic of obstruction were bowel dilation with in creased peristalsis. These authors followed 6 fetuses confirmed at birth to have distal bowel obstruction.…”

Section: Discussionmentioning

confidence: 99%

“…Re cently, reports have also established an asso ciation between fetal echogenic bowel and karyotypic abnormalities or cytomegalovirus (CMV) infection [9][10][11][12][13]. The purpose of this study is to determine which characteristics might distinguish fetuses ultimately having abnormal outcomes in a population at low risk for cystic fibrosis.…”

Section: Introductionmentioning

confidence: 99%

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Fetal Echogenic Bowel on Ultrasound: Is There Clinical Significance?

et al. 1994

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Though echogenic fetal bowel has been associated with meconium ileus and/or peritonitis, it may be a normal finding in the second trimester. The purpose of this study is to determine which characteristics might distinguish fetuses ultimately having abnormal outcomes in a population at low risk for cystic fibrosis. Seven fetuses with echogenic bowel were identified: 5 fetuses ≤ 20 weeks gestation (group 1) and 2 fetuses 20–25 weeks gestation (group 2) at diagnosis. Four of 5 group 1 fetuses had resolution of the echogenic bowel during the second trimester. One group 2 fetus had a persistent mass associated with growth deficiency and trisomy 18. The neonatal bowel evaluation was normal in the remaining 2 fetuses although echogenic findings persisted into the third trimester. In a low-risk population, echogenic bowel usually resolves without neonatal sequelae. Even when persistent into the third trimester, echogenic bowel does not uniformly herald an abnormal outcome. Echogenic bowel coexistent with other abnormalities (such as growth deficiency or structural malformations) may be a comarker for aneuploidy.

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Paralytic ileus in a fetus–neonate after maternal intake of benzodiazepine

1995

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Paralytic ileus of the small bowel was diagnosed in a fetus at 32 weeks' gestation after referral because of polyhydramnios. The mother had taken clonazepam, a benzodiazepine, and carbamazepine during the entire pregnancy for epilepsy. All known causes for the ileus were ruled out and at 20 months the boy has developed normally. We conclude that maternal anticonvulsant drug intake was very likely the cause of the paralytic ileus. This side-effect is known in experimental and clinical pharmacology but has not yet been described in human fetuses.

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Gastrointestinal Tract Obstruction in the Fetus

Cited by 18 publications

References 29 publications

Correlation of Prenatal Ultrasound and Postnatal Outcome in Meconium Peritonitis

Correlation of Prenatal Ultrasound and Postnatal Outcome in Meconium Peritonitis

Fetal Echogenic Bowel on Ultrasound: Is There Clinical Significance?

Paralytic ileus in a fetus–neonate after maternal intake of benzodiazepine

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