Gastroprotective and Antioxidant effect of Petroleum ether Extract of <i>Eupatorium triplinerve</i> Vahl

Kathirvelu, Parimala; Cheriyan, Binoy Varghese; Jagan, N; Viswanathan, S; Kumar, Sathish; Kamalakannan, P.

doi:10.5958/0974-360x.2019.00893.x

Rese. Jour. of Pharm. and Technol.

2019

DOI: 10.5958/0974-360x.2019.00893.x

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Gastroprotective and Antioxidant effect of Petroleum ether Extract of Eupatorium triplinerve Vahl

Parimala Kathirvelu¹,

Binoy Varghese Cheriyan²,

N Jagan³

et al.

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2023

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Cited by 2 publications

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Ayapana triplinervis: An updated review of traditional uses, phytochemistry, and pharmacological activities

Bhattacharyya,

Easmin,

Pal

et al. 2023

Pharmacological Research - Natural Products

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Ayapana triplinervis: An updated review of traditional uses, phytochemistry, and pharmacological activities

Bhattacharyya,

Easmin,

Pal

et al. 2023

Pharmacological Research - Natural Products

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In vitro and In vivo Study of Gastroprotective effect of Purified Extract Andrographis paniculata

Pusmarani,

Dewi,

Juliansyah Putri

et al. 2023

RJPT

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Gastric ulcers are caused by excessive gastric acid secretion, alcohol, and long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs). Aspirin is one of the NSAIDS that can induce peptic ulcers. Traditional medicines that have been proven to have gastroprotective activity is Andrographis paniculata (APAC). The purpose of this study is to assess the antioxidant activity and gastroprotective effect of purified extract of APAC. The herbal treatment was given for 7 days, and on the eighth day, all groups except the negative control (Na CMC 0.5%) were given 1000mg/kgBW of aspirin. Six hours later, the rats were sacrificed and opened for macroscopic examination, pH gastric juice value, the volume of gastric value, ulcer index, and inhibition percentage. Antioxidant studies using 2,2-diphenyl-1-picrylhydrazyl (DPPH) showed that APAC has strong antioxidant activity with IC50 value = 64.54. APAC could reduce the occurrence of gastric ulcers by decreasing gastric pH, ulcer index, and increasing inhibition percentage (P=0.000<0.05). Andrographis paniculata has gastroprotective properties associated with antioxidant activity.

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Gastroprotective and Antioxidant effect of Petroleum ether Extract of Eupatorium triplinerve Vahl

Cited by 2 publications

References 0 publications

Ayapana triplinervis: An updated review of traditional uses, phytochemistry, and pharmacological activities

Ayapana triplinervis: An updated review of traditional uses, phytochemistry, and pharmacological activities

In vitro and In vivo Study of Gastroprotective effect of Purified Extract Andrographis paniculata

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