Gastroschisis Trends and Ecologic Link to Opioid Prescription Rates — United States, 2006–2015

Short, Tyiesha D; Stallings, Erin B.; Isenburg, Jennifer; O’Leary, Leslie A.; Yazdy, Mahsa M.; Bohm, Michele K.; Ethen, Mary K.; Chen, Xiaoli; Tran, Tri; Fox, Deborah; Fornoff, Jane; Forestieri, Nina; Ferrell, Emily; Ramirez, Glenda M; Kim, Jamie; Shi, Jingping; Cho, Sook Ja; Duckett, Kirstan; Nelson, N. B.; Zielke, Katherine; John, Kristen St.; Martin, Brennan; Clark, Carolina; Huynh, My-Phuong; Benusa, Colin; Reefhuis, Jennita

doi:10.15585/mmwr.mm6802a2

Cited by 51 publications

(43 citation statements)

References 7 publications

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“…We identified a small number of cases of gastroschisis (n = 9), although this was a large-scale birth cohort, and the frequency of gastroschisis here observed (1.0/10,000 live births) was within the range of past reports in Japan [3,4]. Therefore, the low number of cases limited data analysis and conclusions being drawn; that is, we could not summarise certain characteristics, such as maternal medication, especially opioid use [28], and could not statistically discuss the differences in frequency of gastroschisis based on the strata of individual characteristics (for example, only 4 cases in the reference BMI group). Nonetheless, we considered that the descriptive data on Japanese gastroschisis frequency in this context was worthy of report, to encourage and contribute to future studies, such as case-control design considered statistical justification of sample size, regarding gastroschisis-related factors among Asians, who have the lower percentage of overweight and obesity compared with Caucasians.…”

Section: Limitationscontrasting

confidence: 58%

Does overweight before pregnancy reduce the occurrence of gastroschisis?: the Japan Environment and Children’s Study

et al. 2020

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Objective: For several observational studies that have reported the factors related to gastroschisis, the target population in these studies was mainly residents of Europe or the US, and there is little data on the Asian population. In this study, we summarised characteristics of Japanese women who delivered infants with gastroschisis, particularly focusing on the pre-pregnancy body mass index (BMI), which was found to be inversely associated with gastroschisis in past studies, because the distribution of BMI is clearly different in Asia and the West. Results:We used data from a nationwide birth cohort study which recruited pregnant women between 2011 and 2014. Among 92,796 women who delivered singleton live births, the frequency of underweight (pre-pregnancy BMI < 18.5 kg/m 2 ) was 16.2%, reference weight (18.5-24.9 kg/m 2 ) 73.1%, and overweight (≥ 25.0 kg/m 2 ) 10.6%. We identified only 9 infants with gastroschisis, 2 of whose women were underweight (frequency of gastroschisis = 0.01%), 5 were in the reference group (0.01%), and 2 were overweight (0.02%). Of these 9 women, none were aged < 20 years, 2 were aged 20-29 years (frequency = 0.01%), and 7 were aged 30-39 years (0.01%). No reduction in the occurrence of gastroschisis was apparent among Japanese women who were overweight before pregnancy.

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Section: Limitationscontrasting

confidence: 58%

Does overweight before pregnancy reduce the occurrence of gastroschisis?: the Japan Environment and Children’s Study

et al. 2020

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“…Of interest, the current data show that neural tube defects are no longer declining, consistent with a recent report (Williams et al, ). Gastroschisis continues to increase in prevalence, although at a less rapid annual percent change (Jones et al, ; Kirby et al, ; Short et al, ). A slight increasing prevalence for Down syndrome when age‐adjusted shows the impact of increasing maternal age on the overall prevalence compared to the nonadjusted age prevalence.…”

Section: Discussionmentioning

confidence: 99%

National population‐based estimates for major birth defects, 2010–2014

Cara

Isenburg

Canfield

et al. 2019

Birth Defects Research

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Background Using the National Birth Defects Prevention Network (NBDPN) annual data report, U.S. national prevalence estimates for major birth defects are developed based on birth cohort 2010–2014. Methods Data from 39 U.S. population‐based birth defects surveillance programs (16 active case‐finding, 10 passive case‐finding with case confirmation, and 13 passive without case confirmation) were used to calculate pooled prevalence estimates for major defects by case‐finding approach. Fourteen active case‐finding programs including at least live birth and stillbirth pregnancy outcomes monitoring approximately one million births annually were used to develop national prevalence estimates, adjusted for maternal race/ethnicity (for all conditions examined) and maternal age (trisomies and gastroschisis). These calculations used a similar methodology to the previous estimates to examine changes over time. Results The adjusted national birth prevalence estimates per 10,000 live births ranged from 0.62 for interrupted aortic arch to 16.87 for clubfoot, and 19.93 for the 12 critical congenital heart defects combined. While the birth prevalence of most birth defects studied remained relatively stable over 15 years, an increasing prevalence was observed for gastroschisis and Down syndrome. Additionally, the prevalence for atrioventricular septal defect, tetralogy of Fallot, omphalocele, and trisomy 18 increased in this period compared to the previous periods. Active case‐finding programs generally had higher prevalence rates for most defects examined, most notably for anencephaly, anophthalmia/microphthalmia, trisomy 13, and trisomy 18. Conclusion National estimates of birth defects prevalence provide data for monitoring trends and understanding the impact of these conditions. Increasing prevalence rates observed for selected conditions warrant further examination.

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“…Gastroschisis is one of the few major birth defects with a documented increasing birth prevalence in both resource-limited and resource-rich settings. In fact, the prevalence of gastroschisis has been increasing worldwide for decades (Bugge et al, 2017;Castilla, Mastroiacovo, & Orioli, 2008;Kazaura et al, 2004;Loane, Dolk, Bradbury, & Group, 2007;Whitehall, Kandasamy, Stalewski, & Gill, 2010) as well as in the United States (B. G. Benjamin, Ethen, Van Hook, Myers, & Canfield, 2010;Chabra, Gleason, Seidel, & Williams, 2011;Collins et al, 2007;Hougland, Hanna, Meyers, & Null, 2005;Jones et al, 2016;Kirby et al, 2013;Laughon et al, 2003;Salemi et al, 2009;Salihu, Pierre-Louis, Druschel, & Kirby, 2003;Short et al, 2019;St Louis et al, 2017;Vo & Langlois, 2015;Vu et al, 2008). Reasons for the increasing prevalence in gastroschisis are unknown; however, several risk factors are associated with this defect, especially young maternal age.…”

Section: Gastroschisismentioning

confidence: 99%

Population‐based birth defects data in the United States, 2012–2016: A focus on abdominal wall defects

Stallings

Isenburg

Short

et al. 2019

Birth Defects Research

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Background/Objectives: In this report, the National Birth Defects Prevention Network (NBDPN) examines and compares gastroschisis and omphalocele for a recent 5-year birth cohort using data from 30 population-based birth defect surveillance programs in the United States. Methods: As a special call for data for the 2019 NBDPN Annual Report, state programs reported expanded data on gastroschisis and omphalocele for birth years 2012–2016. We estimated the overall prevalence (per 10,000 live births) and 95% confidence intervals (CI) for each defect as well as by maternal race/ethnicity, maternal age, infant sex, and case ascertainment methodology utilized by the program (active vs. passive). We also compared distribution of cases by maternal and infant factors and presence/absence of other birth defects. Results: The overall prevalence estimates (per 10,000 live births) were 4.3 (95% CI:4.1–4.4) for gastroschisis and 2.1 (95% CI: 2.0–2.2) for omphalocele. Gastroschisis was more frequent among young mothers (<25 years) and omphalocele more common among older mothers (>40 years). Mothers of infants with gastroschisis were more likely to be underweight/normal weight prior to pregnancy and mothers of infants with omphalocele more likely to be overweight/obese. Omphalocele was twice as likely as gastroschisis to co-occur with other birth defects. Conclusions: This report highlights important differences between gastroschisis and omphalocele. These differences indicate the importance of distinguishing between these defects in epidemiologic assessments. The report also provides additional data on co-occurrence of gastroschisis and omphalocele with other birth defects. This information can provide a basis for future research to better understand these defects.

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Gastroschisis Trends and Ecologic Link to Opioid Prescription Rates — United States, 2006–2015

Cited by 51 publications

References 7 publications

Does overweight before pregnancy reduce the occurrence of gastroschisis?: the Japan Environment and Children’s Study

Does overweight before pregnancy reduce the occurrence of gastroschisis?: the Japan Environment and Children’s Study

National population‐based estimates for major birth defects, 2010–2014

Population‐based birth defects data in the United States, 2012–2016: A focus on abdominal wall defects

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