Gatifloxacin Loaded Nano Lipid Carriers for the Management of Bacterial Conjunctivitis
Poorva H. Joshi,
Ahmed Adel Ali Youssef,
Mihir Ghonge
et al.
Abstract:Bacterial conjunctivitis (BC) entails inflammation of the ocular mucous membrane. Early effective treatment of BC can prevent the spread of the infection to the intraocular tissues, which could lead to bacterial endophthalmitis or serious visual disability. In 2003, gatifloxacin (GTX) eyedrops were introduced as a new broad-spectrum fluoroquinolone to treat BC. Subsequently, GTX use was extended to other ocular bacterial infections. However, due to precorneal loss and poor ocular bioavailability, frequent admi… Show more
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