Abstract. After a short introduction on the low background liquid xenon DAMA set-up (DAMA/LXe) and its main previous results, we discuss the search for the nucleon, di-nucleon and tri-nucleon decays into invisible channels (disappearance or decay to neutrinos, Majorons, etc.) in the 136 Xe isotope. The obtained limits (90% C.L.) on the lifetimes are: τn > 3.3 · 10 23 yr, τp > 4.5 · 10 23 yr, τnp > 3.2 · 10 23 yr, τpp > 1.9 · 10 24 yr, τnnp > 1.4 · 10 22 yr, τnpp > 2.7 · 10 22 yr and τppp > 3.6 · 10 22 yr. In particular, the tri-nucleon decay into invisible channels is investigated here for the first time.