GB Virus C infection in Patients With HIV/Hepatitis C Virus Coinfection: Improvement of the Liver Function in Chronic Hepatitis C

Feng, Yue; Liu, Li; Feng, Yuemei; Zhao, Wenhua; Zheng, Li; Zhang, A-Mei; Song, Yuzhu; Xia, Xueshan

doi:10.5812/hepatmon.14169

Cited by 14 publications

(22 citation statements)

References 19 publications

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“…The increasing of prevalence rate with increasing age in current study could indicate an accumulation risk of infection over time. There was no significant association between HGV /GBV-C infection and history of all parenteral transmission routes (Table 4), and this opposite to the findings by Fogeda et al, 25 and Basaras et al, 26 that prior factors were risk factors for HGV/GBV-C in Spain and Germany.…”

Section: Resultscontrasting

confidence: 58%

Prevalence of Hepatitis G Virus Among Patients With Chronic Liver Disease and Healthy Individuals, Sana'a City-Yemen

et al. 2019

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Hepatitis G virus (HGV) is a newly discovered and enveloped RNA positive-stranded flavivirus-like particle, which has not yet been proven to have major negative effects on liver. Therefore, it is important to estimate the prevalence and risk factors of hepatitis G virus infection in Yemeni viral hepatitis patients and general population to design standard prevention and treatment plans. Screening HGV antibodies among 60 chronic HBV and 144 chronic HCV patients comparing with it's prevalence in 218 healthy controls were carried out. Serum samples were collected and tested for human HGV IgG by commercially available ELISA technique. Demographic data such as gender, age, and risk factors of contracting HGV virus were recorded in predesigned questionnaire. The crude prevalence rate of HGV was 2.8%, female specific rate was 0% and male specific rate was 3.5%. The prevalence of HGV among HBV patients was 0%; HCV was 1.4% while in healthy individuals it was 4.6%. When age groups considered, the prevalence of HGV among age groups 20-29 years and 30-39 years was 3.5%, while in older age groups the rate of HGV was 0%. There was a trend towards increased levels of HGV infection with the second and third decades of life (3.5%). There was no significant association between HGV infection and risk factors of hepatitis viruses. It can be concluded from this study that HGV virus is circulating in the risk groups and in the community in general Yemen, and there is a possibility that this virus may at some time become epidemic if preventive measures are not applied. The risk of community among healthy people more than in risk groups as HBV and HCV patients. Additionally HGV increases with young male adults.

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Section: Resultscontrasting

confidence: 58%

Prevalence of Hepatitis G Virus Among Patients With Chronic Liver Disease and Healthy Individuals, Sana'a City-Yemen

et al. 2019

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“…GBV-C co-infection was associated with an improved prognosis and reduced mortality among HIV-infected patients. GBV-C RNA positivity was also associated with liver function improvement among HCV infected patients (26)(27)(28)(29)(30).…”

Section: Discussionmentioning

confidence: 92%

Prevalence and genotypic distribution of GB virus C and torque teno virus among patients undergoing hemodialysis

Rinonce

Yano

Utsumi

et al. 2017

Molecular Medicine Reports

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Patients undergoing hemodialysis are at increased risk of infection with blood-borne viruses, including GB virus C (GBV-C) and torque teno virus (TTV). However, the prevalence and genotypic distribution of these viruses in the assessed patients undergoing hemodialysis remains unclear. The present study investigated these issues and the possibility of nosocomial transmission among patients undergoing hemodialysis in a unit in Yogyakarta, Indonesia. GBV-C RNA was detected in 92/161 patients (57.1%) by nested reverse-transcription polymerase chain reaction. Phylogenetic analysis of the 5'-untranslated region (UTR) classified the GBV-C isolates into genotypes 6 (85%), 2 (8%), 4 (6%), and 3 (1%). TTV DNA was detected in all patients by the amplification of the 5'-UTR and open reading frame-1 (ORF1) by nested and semi-nested polymerase chain reaction. Phylogenetic analysis based on the ORF1 revealed that genotype 1 was dominant (84%), followed by genotypes 2 (10%) and 3 (6%). The greater prevalence of GBV-C genotype 6 in patients undergoing hemodialysis compared with the general population and the identical sequences observed in multiple isolates provided strong evidence of patient-to-patient transmission. The prevalence of TTV in hemodialysis patients was similar to that observed in the general population, and only one pair of TTV isolates was identical. These results indicated that nosocomial infection was not the main cause of the high prevalence of TTV in patients undergoing hemodialysis. In conclusion, GBV-C and TTV infections are common in patients undergoing hemodialysis in Yogyakarta, Indonesia, and transmission is likely to be nosocomial in the case of GBV-C infection.

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“…Several reasons make burn patients disposed to infection, such as wide exposed raw areas, necrotic tissue presence, immunocompromising effects of burn wound, prolonged hospitalization, patients overcrowding in wards, inability of blood to rich the affected environment and moist area in wound area (which is susceptible for proliferation and colonization) (2,(9)(10)(11)(12)(13). Now it has been proved that 75% of burn injury death is due to infection rather than osmotic shock or hypovolemia and most infection related burn-death is followed by septic shock with alongside bacteremia (2,7,(14)(15)(16).…”

Section: Introductionmentioning

confidence: 99%

“…One of the important facts is the color of lesion and wound, which has been confirmed by several articles. On the other hand, some studies approved that infection in burn patients with a history of important illness like hypertension can be caused by special bacteria like Acinetobacter (8,12,13,(19)(20)(21)(22)(23)(24)(25). Almost all studies approved that Pseudomona aeruginosa is the leading cause of infection in burn injuries.…”

Section: Introductionmentioning

confidence: 99%

Bacteriologic Study in Burn Patients Admitted to Burn Ward of Sina Hospital of Tabriz During 2012 - 2013: A Cross-Sectional Study

Saleh

Afsharjoo

Ramouz

et al. 2015

Arch Clin Infect Dis

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Background:One of the important causes of mortality and morbidity in burn wards is infection. There are several reasons which make burn patients disposed to infection. Objectives: The current study aimed to investigate the role of different factors that affect bacteremia occurrence in burn patients and factors relevant with mortality in these patients. Patients and Methods:This cross-sectional study was performed in one year on 81 burn patients. We collected patient data regarding age, body weight and height, cause of burn, lesion color and place and percentage of burn. Then we documented all interventions, blood tests and cultures and recorded colonies criteria. Results: Thirty-nine males (48.1%) and 42 females (51.9%) included with a mean age of 32.06 ± 17.46 years. In patients without bacteremia, 57 patients did not need catheterization (89.1%), however in patients with bacteremia, nine needed a catheter (52.9%).. In this survey, in patients with bacteremia, 12 survived (70.9%), however in those without bacteremia, 56 patients survived (92.2%). Then, the relativity between the type of burn and wound infection bacteria species was investigated, but analysis found a P value of 0.65, which was not significant. Conclusions: Invasive interventions increased bacteremia susceptibility in burn wards. Mortality rate had a direct association with bacteremia prevalence and increased by larger burn area.

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GB Virus C infection in Patients With HIV/Hepatitis C Virus Coinfection: Improvement of the Liver Function in Chronic Hepatitis C

Cited by 14 publications

References 19 publications

Prevalence of Hepatitis G Virus Among Patients With Chronic Liver Disease and Healthy Individuals, Sana'a City-Yemen

Prevalence of Hepatitis G Virus Among Patients With Chronic Liver Disease and Healthy Individuals, Sana'a City-Yemen

Prevalence and genotypic distribution of GB virus C and torque teno virus among patients undergoing hemodialysis

Bacteriologic Study in Burn Patients Admitted to Burn Ward of Sina Hospital of Tabriz During 2012 - 2013: A Cross-Sectional Study

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