GC-MS profiling, bioactivities and in silico theoretical explanation of cone oil from Pinus thunbergii Parl

Yang, Yi; Meng, Jing; Liu, Chang; Zhang, Yunci; Tian, Jing; Gu, Dongyu

doi:10.1016/j.indcrop.2019.111765

Cited by 8 publications

(5 citation statements)

References 26 publications

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“…Considering the importance of edible oil flavor, many studies have identified the volatile compounds present in oils using gas chromatography-mass spectrometry (GC-MS). [15][16][17] Pacioni et al [18] performed a blind analysis of 18 olive oil samples flavored with white and black truffles from the Italian market using GC-MS and an electronic nose. Madhumita et al [19] detected the major compounds, including eugenol, estragole, linalool, -copaene, anethole, chavicol, and caryophyllene in betel leaf essential oil using GC-MS. Zhang et al [20] analyzed the change in volatile compounds in tuna oil during storage using GC-MS with laser irradiation.…”

Section: Introductionmentioning

confidence: 99%

“…Considering the importance of edible oil flavor, many studies have identified the volatile compounds present in oils using gas chromatography–mass spectrometry (GC–MS). [ 15–17 ] Pacioni et al. [ 18 ] performed a blind analysis of 18 olive oil samples flavored with white and black truffles from the Italian market using GC–MS and an electronic nose.…”

Section: Introductionmentioning

confidence: 99%

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Fatty Acids and Flavor Components in the Oil Extracted from Golden Melon Seeds

Chen

Zhu

et al. 2021

Euro J Lipid Sci & Tech

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For complete utilization of raw materials and edible oil production, the oil from golden melon seeds (GSs) is extracted via the cold‐pressing, hot‐pressing, and ultrasound‐assisted aqueous enzymatic extraction (AEE), and the fatty acid composition, and nutritional value of the extracted GS oils (GSOs) are analyzed. The volatile compounds present in the GSOs are determined using gas chromatography–mass spectrometry. The aroma profiles of different GSO samples are further distinguished by using an electronic nose. A total of 16 fatty acids are identified in the GSO samples, with atherogenic, thrombogenic, and nutritive value indices ranging from 0.142–0.151, 0.366–0.403, and 5.019–5.299, respectively. Moreover, 43 volatile compounds, including esters, hydrocarbons, alcohols, ketones, pyrazines, and aldehydes are identified. The cold‐pressed GSO presents fresh and fruity flavors, while the hot‐pressed GSO presents roasted, nutty, fatty, and fruity flavors, and the GSO obtained via AEE presents fatty and fruity flavors. The acid and peroxide contents of these oil samples are 0.69–079 mg g−1 and 5.17–5.79 mmol kg−1, respectively. The results indicate that the extraction method affects the fatty acid composition, flavor components, and physiochemical properties of the GSO. This study may help promote the development of edible GSO. Practical applications: With high demand for edible oils, it is of great significance to find natural edible oils from different sources. The oil in golden melon seeds is extracted by different methods. Their fatty acid composition and flavor components are analyzed. The GSO extracted via AEE method is rich in fatty acids composition. This work would guide the development of an edible GSO and increase the value of golden melon.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Fatty Acids and Flavor Components in the Oil Extracted from Golden Melon Seeds

Chen

Zhu

et al. 2021

Euro J Lipid Sci & Tech

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“…The affinity of γmuurolene against the active site of α-amylase is moderately strong (-6.90 kcal/mol, Table 3). However, this docking binding score of the same ligand is more favorable than the binding energy (-5.59 kcal/mol) determined by Yang et al (2019) against α-amylase. The 3).…”

Section: Molecular Docking Results Of Essential Oil Major Compoundsmentioning

confidence: 73%

“…In another study, Hertia cheirifolia essential oil, which contains high amounts of αpinene as the major compound, was stated to be a potential αglucosidase inhibitor (Majouli et al, 2016). In a molecular docking study conducted by Yang et al (2019), it was stated that the binding score of α-pinene to α-amylase was high, while in the same study, it was stated that the binding scores were low for caryophyllene and cadinene. Although there are some reports in the literature that some plant species containing terpinen-4-ol as the main component exhibit remarkable α-amylase and α-glucosidase inhibitory activities (Bouyahya et al, 2020;Usman et al, 2020) viridiflorol is not mentioned.…”

Section: α-Amylase and α-Glucosidase Inhibitory Activity Potential Of...mentioning

confidence: 99%

“…Figure 3. Top-ranked conformations of γ-muurolene (A-α-amylase, B-AChE, C-BChE, D-Tyrosinase)better binding affinity scored by AutoDock Vina program compared with the score found byYang et al (2019) shows that AutoDock Vina has a more optimized scoring function than the AutoDock 4.2, and thus can identify energetically more favorable binding conformations in the active site of the α-amylase. The top-ranked conformation of γ-muurolene in the inhibitor binding cavity of the human AChE enzyme is given in Figure3B.…”

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confidence: 98%

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Chemical composition and cholinesterase, tyrosinase, alpha-amylase and alpha-glucosidase inhibitory activity of the essential oil of Salvia tomentosa

Kocer,

Istıfli

2021

Int. J. Plant Based Pharm.

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The aim of this study was to determine the chemical composition of Salvia tomentosa (Miller) essential oil and to examine its inhibitory effect on acetylcholinesterase (AChE), butyrylcholinesterase (BChE), tyrosinase, α-amylase and α-glucosidase in vitro. In this study, the interaction between the main components of essential oil and the enzymes in question was analyzed through molecular docking analyses. The presence of 60 compounds representing 98.2% of the essential oil was determined. The major compounds of the oil were camphor (9.35%), γ-muurolene (8.37%), α-pinene (7.59%), α-caryophyllene (6.25%), viridiflorol (5.13), δ-cadinene (5.01%), and terpinene-4-ol (5.01 %). The oil exhibited higher inhibitory activity on BChE than on AChE. The BChE inhibitory activity of the oil was determined to be 16.48 mg GALAEs/g. The oil showed 47.13 mg KAEs/g inhibitory activity on tyrosinase. The inhibitory activities of the essential oil on α-glucosidase and α-amylase were determined as 703.29 and 694.75 mg ACEs/g, respectively. Based on docking binding energies, δ-cadinene, viridiflorol, γ-muurolene and α-caryophyllene were determined to be the most promising ligands showing the highest affinity (min. -6.90 kcal/mol; max. -8.40 kcal/mol) against α-amylase, AChE and BChE. However, all four ligands were found to exhibit low affinity (min. -5.50 kcal/mol; max. -5.90 kcal/mol) against tyrosinase. Considering in silico physicochemical properties, drug-like features (Lipinski's rule of 5) and intracellular targets, δ-cadinene, viridiflorol, γ-muurolene and α-caryophyllene possess hit features and do not show non-specific enzyme or protein affinity. Ligand binding assays (LBA) to be performed between the monoterpenes and enzymes in question may constitute the next step in confirming their competitive inhibitory capacity.

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De novo assembly of the Mylia taylorii transcriptome and identification of sesquiterpene synthases

Xia

Liang

et al. 2021

Archives of Biochemistry and Biophysics

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GC-MS profiling, bioactivities and in silico theoretical explanation of cone oil from Pinus thunbergii Parl

Cited by 8 publications

References 26 publications

Fatty Acids and Flavor Components in the Oil Extracted from Golden Melon Seeds

Fatty Acids and Flavor Components in the Oil Extracted from Golden Melon Seeds

Chemical composition and cholinesterase, tyrosinase, alpha-amylase and alpha-glucosidase inhibitory activity of the essential oil of Salvia tomentosa

De novo assembly of the Mylia taylorii transcriptome and identification of sesquiterpene synthases

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