Gd-dtpa as an alternative contrast agent in conventional and interventional radiology

Abstract

Gd-DTPA may be used as an alternative contrast medium in selected conventional and interventional roentgenological studies when iodine is contra-indicated.

Are Gadolinium-based Contrast Media Really Safer than Iodinated Media for Digital Subtraction Angiography in Patients with Azotemia?

“…On the other hand, gadolinium-based contrast media are regarded as nonnephrotoxic in clinically recommended doses for magnetic resonance (MR) imaging and MR angiography (2). Gadolinium chelates have thus been advocated (3)(4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14) as safer than iodinated media in patients with azotemia who are undergoing x-ray angiography with digital subtraction technique (ie, digital subtraction angiography [DSA]) for endovascular diagnostic and therapeutic purposes.…”

Einsatz von niederosmolarem Gadolinium zur angiographischen Darstellung und bei interventionell-radiologischen Eingriffen bei niereninsuffizienten Patienten

“…Andere mögliche Indikationen sind Unverträglichkeit gegenüber jodhaltigem Kontrastmittel, Schilddrüsenüberfunktion oder geplante Radiojodtherapie bei Schilddrüsenmalignom [27]. Vehmas u. Markkola berichten über 8 Patienten, denen wegen Jodallergie Gadolinium-DTPA für gastrointestinale und urologische Interventionen (ERCP, PTCD, retrograde Urographie, Nephrostomie) verabreicht wurde [28]. In der Computertomographie vermag Gadolinium die Gefäûe in Thorax und Abdomen hinlänglich darzustellen.…”

Gadolinium-Enhanced Digital Subtraction Angiography of Hemodialysis Fistulas: A Diagnostic and Therapeutic Approach

“…Gadolinium chelates have also been used in patients with a history of allergiclike reactions to iodinated contrast agents as an alternative radiographic contrast agent, initially for CT [11,12] and then for digital subtraction angiography [13]. Gadolinium chelates have also been proposed as a contrast agent for angiography [14] and for various types of interventional procedures in patients with renal insufficiency [15][16][17], but until now, little experience with hemodialysis fistulas has been reported [18]. The aim of our study was to evaluate the feasibility, safety, and reliability of a gadolinium-based complex as a contrast agent for opacification of arteriovenous fistulas in diagnostic procedures or before percutaneous transluminal angioplasty.…”