2022
DOI: 10.1039/d2dt00066k
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GdIII and GaIII complexes with a new tris-3,4-HOPO ligand as new imaging probes: complex stability, magnetic properties and biodistribution

Abstract: The development of metal-based multimodal imaging probes is a highly chalenging field in coordination chemistry. In this context, we have developed a bifunctonal hexadentate tripodal ligand (H3L2), with three 3,4-HOPO...

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Cited by 4 publications
(2 citation statements)
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“…In this context, less toxic and biofriendly Mn­(II) complexes have been the focus of the development of next-generation MRI CAs. , Naturally, Mn­(II) also exhibits toxicity when applied to high concentrations; therefore, Mn­(II) complexes must be stable and inert. Tóth et al studied the stability and magnetic properties of magnetic complexes and achieved rich results and provided researchers with testing methods. Three-photon absorption (3PA) materials have made significant progress, especially after the introduction of transition metal centers in 3PA materials, promoting electron transfer and improving nonlinear optical (NLO) activity. , We assumed that manganese complexes have multiphoton absorption properties (long-wave excitation and short-wave emission), thereby providing a deeper tissue penetration depth, which will reduce the damage of light to the tissue and improve the imaging resolution …”
Section: Introductionmentioning
confidence: 81%
“…In this context, less toxic and biofriendly Mn­(II) complexes have been the focus of the development of next-generation MRI CAs. , Naturally, Mn­(II) also exhibits toxicity when applied to high concentrations; therefore, Mn­(II) complexes must be stable and inert. Tóth et al studied the stability and magnetic properties of magnetic complexes and achieved rich results and provided researchers with testing methods. Three-photon absorption (3PA) materials have made significant progress, especially after the introduction of transition metal centers in 3PA materials, promoting electron transfer and improving nonlinear optical (NLO) activity. , We assumed that manganese complexes have multiphoton absorption properties (long-wave excitation and short-wave emission), thereby providing a deeper tissue penetration depth, which will reduce the damage of light to the tissue and improve the imaging resolution …”
Section: Introductionmentioning
confidence: 81%
“…A 3,4-HOPO-based tripodal ligand 33 (Fig. 14) was designed and developed by Chaves et al 62 The coordination behavior of ligand 33 was studied towards Gd 3+ and Ga 3+ through solution thermodynamics. Results from the potentiometric and spectrophotometric titrations suggested the formation of 1 : 1 metal–ligand complexes with the Ga 3+ complex having higher stability than the Gd 3+ complex (log β = 14.3 for Gd 3+ and log β = 26.2 for Ga 3+ ).…”
Section: Detection Of Other Significant Metals and Anions By Hopo Che...mentioning
confidence: 99%