“…The parameter values used for the simulation of the drug release from this device, taken from [18], are stated in Table 1; C 0 denotes the initial concentration of dissolved drug and m 0,p , a 0,p stand for the initial mass and area of each particle of solid drug, respectively, whereas Num is the total number of particles in the device, which we assumed evenly distributed. The diffusion coefficients D ap40 and D ap60 correspond to a liberation media with 40% and 60% ethanol in water, respectively, and k D is the dissolution rate of the particles of solid drug.…”