GDM and Nutrition—Answered and Unanswered Questions—There’s More Work to Do!

Simmons, David

doi:10.3390/nu11081940

Cited by 12 publications

(11 citation statements)

References 23 publications

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“…Gestational diabetes Mellitus (GDM) is one of the urgent medical problems in the world. The management of GDM still poses many unanswered questions 13 . The restriction of dietary carbohydrate (CHO) has been started for the treatment of GDM at a century ago 14 .…”

Section: Mellitusmentioning

confidence: 99%

Are mice born normally with an egg-only diet?

Isobe

Sato²,

Ono³

et al. 2020

Preprint

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Chicken eggs (egg) contain high amounts of important proteins and fat with a very low amount of 2 carbohydrates, and also contain all vitamins and minerals needed for the chick to develop. We mated 8-week-old mice consuming an egg-only diet, and examined whether mice got pregnant and mice gave birth. Then we continued to raise newborn mice only consuming an egg-only diet compared to normal chew diet. We found that the rate of pregnancy of the mice consuming an egg-only diet was not different from that of the mice consuming normal chew diet. Further, we found that the number of pupus born from the mother consuming only eggs was not different from that of the mother consuming normal chew diet. However, the newborn mice from the mother fed only eggs did not grow healthy when they consume egg-only diet. Only few mice were alive at one month after birth. Then we change the diet just before or just after birth from egg only diet to normal chew diet and we found that both group grew healthy more than one month. These results indicate that mice are born healthy only with egg only diet.

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Section: Mellitusmentioning

confidence: 99%

Are mice born normally with an egg-only diet?

Isobe

Sato²,

Ono³

et al. 2020

Preprint

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“…Another metaanalysis assessing a wide variety of diets and pharmaceutical interventions found a possible benefit of metformin on gestational diabetes prevention in obese women [22]. Metformin was found to be associated with an increased weight in offspring when they were exposed prenatally to the drug [23].…”

Section: Discussionmentioning

confidence: 99%

Mediterranean Diet and Metformin Effects on Gestational Diabetes: A Review and Meta-Analysis of Randomized Controlled Trials

Alatawi

2022

JPRI

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Gestational diabetes (GD) is a common and deadly disorder with deleterious effects on both the mother and fetus. The current review assessed the role of the Mediterranean diet and metformin in the prevention of GD. The PubMed, Medline, and Google Scholar databases were searched for relevant articles, and the keywords metformin, Mediterranean diet, and gestational diabetes prevention were used with the proteans AND and OR. Out of the 252 articles retrieved, 48 full texts were assessed, and only nine articles fulfilled the inclusion and exclusion criteria. A data extraction sheet was used to collect the author's name, year of publication, country, methods of the study, risk reduction, odds ratio, relative risk, 95% CI, and P values. Three (33.3%) articles assessed the effectiveness of metformin on GD, and another six (66.7%) investigated the effects of the MedDiet on GD. The studies on metformin showed no reduction in GD (odds ratio, 1.07, 0.79–1.44, P value for overall effect=0.65, I2 for heterogeneity=3%, P value=0.36. Chi-square=2.07, and the mean difference=2), while studies on the MedDiet showed a reduction in gestational diabetes risk ((odds ratio, 0.49, -0.32–0.73, P value for heterogeneity =0.0004, heterogeneity, I =278%, P value for overall effect=0.0005, Chi-square=22.40 and mean difference=5. The Mediterranean diet was effective in the prevention of GD; however, metformin showed no significant risk reduction as an interventional measure.

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“…Obese elderly women have an increased risk of gestational diabetes, which may lead to maternal hypertension, premature rupture of membranes, oligohydramnios, and fatal distress. [14][15][16] Obesity during pregnancy is a high risk factor for GDM. In this study, the perinatal outcome of GDM women was analyzed.…”

Section: Discussionmentioning

confidence: 99%

“…Obese elderly women have an increased risk of gestational diabetes, which may lead to maternal hypertension, premature rupture of membranes, oligohydramnios, and fatal distress. 14 - 16 …”

Section: Discussionmentioning

confidence: 99%

Improved support vector machine algorithm based on the influence of Gestational Diabetes Mellitus on the outcome of perinatal outcome by ultrasound imaging

Liu

2021

Pak J Med Sci

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Objectives: In order to understand the incidence and epidemiological characteristics of gestational diabetes mellitus, the ultrasound imaging of support vector machine processing algorithm was used to clarify the outcome of maternal and neonatal gestational diabetes mellitus. Methods: This study selected clinical data of 12,190 pregnant women who were hospitalized for delivery, and were divided into diabetic group (1268 cases) and control group (10922 cases) according to the diagnosis of gestational diabetes. The study was conducted from January 1, 2012 to December 31, 2019. Colour Doppler ultrasound was performed to record fatal umbilical artery and brain the middle arteries and uterine arteries which are effective indicators of measuring fatal intrauterine conditions. Chi-square test was used to compare the rates between groups, and multivariate logistic regression was used for labour outcomes. Results: The incidence of diabetes during pregnancy is about 10.4% (1268/12190). Senior citizens and women suffering from obesity increase the risk of gestational diabetes, maternal hypertension disorders in pregnancy, premature rupture of membranes, oligohydramnios, fatal distress, multiple births, malpresentation risk increased significantly (P<0.05) than the control group. In gestational diabetes caesarean section rate was significantly higher (61.0% vs46.4%). Caesarean new born 5-minute Apgar score was significantly lower than the control group (P<0.05). Conclusion: In maternal gestational diabetes in high risk pregnancies, complications of pregnancy significantly increase the importance of enhancing weight management and blood glucose monitoring to reduce complications. doi: https://doi.org/10.12669/pjms.37.6-WIT.4855 How to cite this:Liu H, Liu J. Improved support vector machine algorithm based on the influence of Gestational Diabetes Mellitus on the outcome of perinatal outcome by ultrasound imaging. Pak J Med Sci. 2021;37(6):1625-1629. doi: https://doi.org/10.12669/pjms.37.6-WIT.4855 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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GDM and Nutrition—Answered and Unanswered Questions—There’s More Work to Do!

Cited by 12 publications

References 23 publications

Are mice born normally with an egg-only diet?

Are mice born normally with an egg-only diet?

Mediterranean Diet and Metformin Effects on Gestational Diabetes: A Review and Meta-Analysis of Randomized Controlled Trials

Improved support vector machine algorithm based on the influence of Gestational Diabetes Mellitus on the outcome of perinatal outcome by ultrasound imaging

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