Gelatin as It Is: History and Modernity

Михайлов, О. В.

doi:10.3390/ijms24043583

Cited by 44 publications

(30 citation statements)

References 275 publications

(524 reference statements)

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“…The existence of traces of sulfur in the biopolymer-modified polypropylene fabrics is another clue on the formation of bonds between gelatin or sericin and the plasma-irradiated PP fabrics. 46…”

Section: Resultsmentioning

confidence: 99%

Biopolymer-loaded plasma-mediated multi-functional finishes of polypropylene fabrics

Abou-Taleb,

El-Sayed

2024

Polymers from Renewable Resources

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Polypropylene (PP) has unique competitiveness with other synthetic fibers due to its suitable spinnability, availability of raw materials, and low processing cost. PP fabric exhibits excellent chemical, physical, and mechanical properties, such as a light texture, adequate tensile strength, and resistance to most chemicals. However, the absence of reactive functional groups in PP fiber, besides its high crystallinity, results in hydrophobic surface, low affinity to dyestuffs, and poor antistatic properties, which restrict its use in the clothing field. Herein, a water- and energy-saving, eco-friendly finish is proposed to render PP desired properties suitable for textile applications. The surface of PP fabric was activated using oxygen and nitrogen plasma radiations. The plasma-irradiated PP fabric was post-treated with two renewable eco-friendly proteinic biopolymers, namely gelatin and sericin, in the presence and absence of a crosslinking agent. The effects of different process conditions on the properties of the modified PP, including the duration of plasma exposure, the concentration of biopolymer, and treatment temperature were monitored. The affinity of the treated PP fabric towards anionic and cationic dyes was evaluated. The findings of this study demonstrated that the comfort attributes of the plasma/biopolymer-finished fabrics, such as the induced antistatic properties, wettability, and ultraviolet protection, were remarkably improved. The plasma-mediated biopolymer-finished PP fabrics were found dyeable with cationic and anionic dyes. The change in the chemical and morphological structures of PP fabrics was monitored using Fourier transform infrared spectroscopy, scanning electron microscopy, and energy dispersive X-ray spectroscopy.

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Section: Resultsmentioning

confidence: 99%

Biopolymer-loaded plasma-mediated multi-functional finishes of polypropylene fabrics

Abou-Taleb,

El-Sayed

2024

Polymers from Renewable Resources

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“…A successful PDA coating endows the fibrous PCL/GT surface with improved physicochemical properties, as evidenced by the variances in measurements of ζ-potential, water contact angle, and protein adsorption (Figure 2E−G). Type B gelatin at pH 7.0 is usually negatively charged; 28 thus, it is reasonable for PCL/GT to show a negative surface charge of −(35.6 ± 2.1) mV. Since PDA contains a large number of negatively charged phenolic hydroxyl groups, 29 the negative charge density was further increased to −(54.9 ± 3.1) mV (Figure 2E).…”

Section: Pda Coating Of the Electrospunmentioning

confidence: 98%

Pro-vasculogenic Fibers by PDA-Mediated Surface Functionalization Using Cell-Free Fat Extract (CEFFE)

Li,

et al. 2024

Biomacromolecules

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Formation of adequate vascular network within engineered three-dimensional (3D) tissue substitutes postimplantation remains a major challenge for the success of biomaterialsbased tissue regeneration. To better mimic the in vivo angiogenic and vasculogenic processes, nowadays increasing attention is given to the strategy of functionalizing biomaterial scaffolds with multiple bioactive agents. Aimed at engineering electrospun biomimicking fibers with pro-vasculogenic capability, this study was proposed to functionalize electrospun fibers of polycaprolactone/gelatin (PCL/ GT) by cell-free fat extract (CEFFE or FE), a newly emerging natural "cocktail" of cytokines and growth factors extracted from human adipose tissue. This was achieved by having the electrospun PCL/GT fiber surface coated with polydopamine (PDA) followed by PDA-mediated immobilization of FE to generate the pro-vasculogenic fibers of FE-PDA@PCL/GT. It was found that the PDA-coated fibrous mat of PCL/GT exhibited a high FE-loading efficiency (∼90%) and enabled the FE to be released in a highly sustained manner. The engineered FE-PDA@PCL/GT fibers possess improved cytocompatibility, as evidenced by the enhanced cellular proliferation, migration, and RNA and protein expressions (e.g., CD31, vWF, VE-cadherin) in the human umbilical vein endothelial cells (huvECs) used. Most importantly, the FE-PDA@PCL/GT fibrous scaffolds were found to enormously stimulate tube formation in vitro, microvascular development in the in ovo chick chorioallantoic membrane (CAM) assay, and vascularization of 3D construct in a rat subcutaneous embedding model. This study highlights the potential of currently engineered pro-vasculogenic fibers as a versatile platform for engineering vascularized biomaterial constructs for functional tissue regeneration.

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“…The porous nature of gelatin allows for both solvents and solutes to permeate its surface upon contact with an aqueous solution, resulting in its swelling. [ 79 ] Its high water‐absorption capability also serves as a foundation for biogel formation. However, gelatin lacks a stable triple‐helix structure, causing gelatin hydrogels to experience a decrease in mechanical strength.…”

Section: Hydrogel Meniscal Biomaterialsmentioning

confidence: 99%

Advanced Hydrogel Material for Meniscus Repair

Li,

Deng,

Yang

et al. 2024

Adv Funct Materials

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The foundation of regenerative medicine is the investigation and progression of hypotheses and approaches for substituting, mending, reconstructing, or regenerating different tissues and organs within the human body. Nevertheless, due to the slender central segment and the entire unattached configuration of the meniscus, the efficacy of conventional therapies is unsatisfactory in reinstating meniscal health and functionality. To overcome these limitations, medical‐type hydrogels have the potential to provide a solution for meniscus repair and regeneration. Their biocompatibility and modifiability enable safe implantations in vivo, effectively modifying the pathophysiology of cells and the surrounding microenvironment at the site of meniscal injury. This article reviews the usage of different implantable medical‐type hydrogels in meniscal regeneration and repair. First, the structure and physiologic function of the meniscus are first briefly described. Following this, the use of varying hydrogels in meniscus repair is highlighted, alongside a discussion of different materials employed in constructing hydrogel implants. Lastly, an analysis of the issues and challenges associated with hydrogels in meniscus repair is presented.

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Gelatin as It Is: History and Modernity

Cited by 44 publications

References 275 publications

Biopolymer-loaded plasma-mediated multi-functional finishes of polypropylene fabrics

Biopolymer-loaded plasma-mediated multi-functional finishes of polypropylene fabrics

Pro-vasculogenic Fibers by PDA-Mediated Surface Functionalization Using Cell-Free Fat Extract (CEFFE)

Advanced Hydrogel Material for Meniscus Repair

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