Gelation in physically associating biopolymer systems

Carnali, J. O.

doi:10.1007/bf00701120

Cited by 49 publications

(34 citation statements)

References 47 publications

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“…Indeed, it has been suggested in the literature (Carnali, 1992;Baird, 1986) that xanthan molecules ning behavior, high storage modulus, etc. ), it is clear that xan- droplet size distribution is shown in Figure 7b.…”

Section: Resultsmentioning

confidence: 96%

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Oscillatory, creep and steady flow behavior of Xanthan‐thickened oil‐in‐water emulsions

Pal

1995

AIChE Journal

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Section: Resultsmentioning

confidence: 96%

“…The unique physical and rheological properties of xanthan gum are responsible for its widespread use in various applications (Rochefort and Middleman, 1987;Carnali, 1992;Carriere et al, 1993). oil (trade name EDM) supplied by Monarch Oil Company, Canada.…”

Section: Introductionmentioning

confidence: 99%

Oscillatory, creep and steady flow behavior of Xanthan‐thickened oil‐in‐water emulsions

Pal

1995

AIChE Journal

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“…There are also a variety of polysaccharides that form helical structures and thus are stronger materials. In this study, we used four different gelforming polysaccharides: ι-carrageenan, κ-carrageenan, xanthan gum, and konjac gum [24][25][26]. The two carrageenans and xanthan form strong double helical confor-mations with specific cations present [27,28], and konjac forms a partially-ordered single helix with the right carbocation [29].…”

Section: Introductionmentioning

confidence: 99%

“…Gel formation is a two-step process induced by specific counterions; first the double helices aggregate, then the aggregates combine at a certain combination of temperature and concentration, stiffening the gel. Konjac and xanthan gum gel formation seems to be dependent mostly on ionic strength (which also drives helix formation), concentration, and temperature [24,25].…”

Section: Introductionmentioning

confidence: 99%

Biodegradable Polysaccharide Gels for Skin Scaffolds

Juris¹,

Mueller²,

Smith³

et al. 2011

JBNB

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“…[7][8][9] The combination of specific synthetic and natural polymers can create significant synergistic effects as a result of interaction between different polymeric chains and the formation of mixed bonding areas. 10) Synthetic polymers are widely used in pharmaceutical and biomedical applications. However, mixtures of synthetic and natural polymers are increasingly used as a complementary alternative in these areas.…”

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confidence: 99%

Rheological Study of Binary Gels with Carbopol UltrezTM 10 and Hyaluronic Acid

Jiménez¹,

Fresno²,

Ramírez³

2007

CHEMICAL & PHARMACEUTICAL BULLETIN

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Many products containing natural, semi-synthetic and synthetic polymers are used in the pharmaceutical industry as agents for gelling, thickening, stabilizing and modification of viscosity. The polymer materials used to develop pharmaceutical vehicles of topical application must have the appropriate physical, chemical and mechanical properties. Generally, commercialized synthetic polymers comply with these requirements and they are widely used as bases for topical application, but they are not sufficiently biocompatible. The properties of these materials can be improved by combining biological macromolecules such as collagen, elastin and glycosaminoglycans. 1,2)Many semi-solid pharmaceutical vehicles include more than one polymer in the formulation in order to obtain the appropriate properties for topical application. The properties of most of these systems correspond to those of the individual polymers. However, in some cases, the characteristics of the compound systems are superior to those of each of the separate components or they are even qualitatively different. Specifically, the combination of certain synthetic and natural polymers can lead to significant synergistic effects as a result of interaction between the different polymer chains and the formation of mixed bonding areas. 3,4) Mixtures of two or more polymers can show complex properties that depend on the total polymer concentration, the relative proportion of each of the components, the characteristics of the dissolution medium and the temperature. The causes of this non-additive behavior are directly related to the efficiency of the interactions observed among the polymer molecules and to the balance of interaction between the molecules in the same polymer and in different polymers, which depend on the primary and secondary structures in the chains. 5,6) This behavior leads to a wide variety of structural conditions and to the nonlinearity of the macroscopic properties observed in certain compound systems. In fact, the combination of two polymers can produce gels characterized by a higher degree of rigidity than is calculated using a linear combination of rigidity values for gels formed by each of the individual polymers. Many polymers show this non-additive behavior, which is called synergy. 7-9)The combination of specific synthetic and natural polymers can create significant synergistic effects as a result of interaction between different polymeric chains and the formation of mixed bonding areas. 10)Synthetic polymers are widely used in pharmaceutical and biomedical applications. However, mixtures of synthetic and natural polymers are increasingly used as a complementary alternative in these areas. Characterization of these mixtures reveals the existence of synergistic effects that can be used to optimize drug delivery. The advantage of these systems is that the kinetics of drug release from the matrix can be adjusted by varying the composition of the components. 11)However, some types of restructuring observed in some compound polymer systems ...

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Gelation in physically associating biopolymer systems

Cited by 49 publications

References 47 publications

Oscillatory, creep and steady flow behavior of Xanthan‐thickened oil‐in‐water emulsions

Oscillatory, creep and steady flow behavior of Xanthan‐thickened oil‐in‐water emulsions

Biodegradable Polysaccharide Gels for Skin Scaffolds

Rheological Study of Binary Gels with Carbopol UltrezTM 10 and Hyaluronic Acid

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