Gemcitabine and Carboplatin (Renally Dosed) Regimen for Bladder Cancer

Pritchard, Erica; Waddell, J. Aubrey; Solimando, Dominic A.

doi:10.1310/hpj5002-103

Cited by 2 publications

(3 citation statements)

References 21 publications

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“…82 If the latter is used, the proper patient weight and serum creatinine are essential when estimating GFR for use in the Calvert formula to produce the most accurate value. The following guidelines are recommended: 83 If the patient is not overweight or obese (body mass index (BMI) < 25), actual body weight should be used for CrCl calculation. 84–86 If the patient is overweight or obese (BMI ≥25), use an alternate weight descriptor per institution policy (see step 3) for CrCl calculation.…”

Section: Resultsmentioning

confidence: 99%

Creation and evaluation of a cancer chemotherapy order review guide for use at a community hospital

Punke

Waddell

2017

J Oncol Pharm Pract

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The proper evaluation of cancer chemotherapy orders is necessary for patients to receive safe and effective treatment. The chemotherapy treatment setting is evolving resulting in hospital pharmacists without extensive oncology training or experience now being responsible for evaluation of chemotherapy orders. The primary objective was to create a step-by-step chemotherapy order evaluation guide with a detailed explanation for each step. The secondary objective was to evaluate non-oncology trained pharmacists' ability to accurately review simulated chemotherapy orders post-education using the guide. A two-page chemotherapy order evaluation guide was created based on an accepted method of chemotherapy order review consisting of the following eight steps: regimen verification, clinical trial protocol verification, body surface area calculation, dose calculation, laboratory values, emesis prophylaxis, adjunctive or supportive care measures, and pharmacy labels. A literature search was performed for each step. A detailed explanation for each step was written as a separate component from the guide to encompass the literature search information and current guidelines in a more comprehensive manner. Non-oncology trained community hospital pharmacists were educated on use of the guide for approximately 30 min. The guide was evaluated using timed simulated chemotherapy orders pre- and post-education consisting of a general chemotherapy order and a carboplatin dosing order. Nineteen pharmacists were tested with simulated chemotherapy orders. A significant difference was detected between the pre- and post-education for both the general chemotherapy (p = 0.00032) order and carboplatin dosing order (p = 0.031).

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Section: Resultsmentioning

confidence: 99%

Creation and evaluation of a cancer chemotherapy order review guide for use at a community hospital

Punke

Waddell

2017

J Oncol Pharm Pract

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“…In the present case, because liver metastasis was TCC, chemotherapy was administered according to treatment protocols for bladder cancer [7]. The patient survived for 2 months after chemotherapy.…”

Section: Discussionmentioning

confidence: 99%

“…Eleven months post-operation, space-occupying lesion in S5 of the liver was detected by CT. Percutaneous biopsy of the hepatic lesion indicated metastasis of the TCC. The patient was intravenously treated with chemotherapy as follow regimen: gemcitabine 1000 mg/m 2 (on days 1 and 8) and carboplatin area under the curve = 5 (on day 1) according to treatment protocols for bladder cancer [7]. Two months after receiving chemotherapy, the size of the hepatic tumor increased and her general condition deteriorated.…”

Section: Presentation Of Casementioning

confidence: 99%