Gender differences in adult-onset asthma: results from the Swiss SAPALDIA cohort study

Hansen, Sofie; Probst‐Hensch, Nicole; Keidel, Dirk; Dratva, Julia; Bettschart, Robert; Pons, Marco; Burdet, Luc; Bridevaux, Pierre‐Olivier; Schikowski, Tamara; Schindler, Christian; Rochat, Thierry; Zemp, Elisabeth

doi:10.1183/13993003.02278-2014

Cited by 33 publications

(32 citation statements)

References 38 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…24,25 Self-reported nasal allergy was an overall risk factor for incident asthma. 12 This is consistent with our findings, where males with asthma were sensitized to a greater extent than females. In males, but not females, Atopy was a risk factor, although these results must be interpreted with caution due to the few incident cases.…”

Section: Discussionsupporting

confidence: 93%

“…9,10 Several studies have shown gender differences in incidence, prevalence, diagnosis and severity of asthma, 11,12 and also differences in perception and behavior are described. 9,10 Several studies have shown gender differences in incidence, prevalence, diagnosis and severity of asthma, 11,12 and also differences in perception and behavior are described.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Risk factors for incident asthma and COPD in a cohort of young adults

Traulsen

Bælum

Halling

et al. 2017

Clinical Respiratory J

View full text Add to dashboard Cite

show abstract

Section: Discussionsupporting

confidence: 93%

Section: Introductionmentioning

confidence: 99%

Risk factors for incident asthma and COPD in a cohort of young adults

Traulsen

Bælum

Halling

et al. 2017

Clinical Respiratory J

View full text Add to dashboard Cite

show abstract

“…A higher incidence of asthma among females in the adult population is described, [5][6][7] yet our figures are higher than generally reported. We are a tertiary level facility, and preferentially follow up patients whose asthma is difficult to control.…”

Section: Discussioncontrasting

confidence: 55%

Factors affecting compliance and control of asthma in patients attending the Respiratory Outpatient Department, Chris Hani Baragwanath Academic Hospital

et al. 2015

View full text Add to dashboard Cite

Asthma is a chronic, inflammatory airway disease involving airway hyper-responsiveness and intermittent airflow obstruction. Although potentially under-reported, asthma affects 20% of people in sub-Saharan Africa. [1] There is a wide range in prevalence among different geographic locations, owing in part to poverty, climate, and allergen exposure. [1] There appears to be a racial discrepancy in prevalence of asthma, with Asians being less affected than Native Americans, and a gender discrepancy, with a female preponderance among adult asthmatics. [2] Patients with asthma over the age of 65 years tend to fare worse than younger patients. [3] Identification of the level of severity of asthma and determination of the factors affecting asthma control are crucial to the design and implementation of strategies to reduce the number of exacerbations and hospital admissions, thus improving outcomes. Of vital importance is the documentation of important parameters in the management of asthma, particularly in a public hospital where patients often see different doctors at each visit. These include inhaler technique, frequency of exacerbations and number of admissions to hospital.Our impression is that the control of asthma in patients attending the Respiratory Outpatient Department (ROPD) at Chris Hani Baragwanath Academic Hospital (CHBAH), Johannesburg, is suboptimal. However, no study has been performed at our hospital to interrogate this hypothesis, or to quantify the proportion of our patients with severe disease and/or poor control. We are of the opinion that these data will provide important information on asthma management relevant to the South African (SA) healthcare system. MethodsWe undertook a retrospective analysis of scheduled visits by patients with asthma attending the ROPD at CHBAH. Data collected included demographics, symptoms, disease severity, medication prescription and usage, control of asthma, inhaler technique competency and spirometry. This information was captured by the investigator using a data collection sheet that is routinely completed as part of our patients' clinic records. The sources of information were the patients' files, held at ROPD.Definitions of asthma control and indicators of asthma severity were based on those advocated by local SA Thoracic Society guidelines. [4] Acute exacerbations and severity were determined by the need for oral steroid use, days off work, antibiotic use, number of Emergency Department visits (exacerbations), intensive care unit admissions and general ward ORIGINAL RESEARCHBackground. There is a sense among respiratory physicians that asthma is poorly controlled in public sector hospitals, possibly due to poor adherence and lack of knowledge regarding inhaler technique. Objective. To describe the status of asthma control in patients attending the Respiratory Outpatient Department at Chris Hani Baragwanath Academic Hospital. Methods. A retrospective record review was conducted on outpatient files of asthmatics known to the Respiratory Department. Data obtained...

show abstract

“…Because of the gender differences in asthma onset and respiratory symptoms (Hansen et al, 2015;Takeda et al, 2013), we stratified the allele frequencies and genotypes by gender. However, no statistically significant differences in genotype or allele frequency distribution were found for rs2228145 and rs12083537 between patients and controls in either males or females (supporting Tables 1 and 2).…”

Section: The Genotype and Allele Frequency Distributions In Patients mentioning

confidence: 99%

The IL6R gene polymorphisms are associated with sIL-6R, IgE and lung function in Chinese patients with asthma

Wang

et al. 2016

Gene

View full text Add to dashboard Cite

Gender differences in adult-onset asthma: results from the Swiss SAPALDIA cohort study

Cited by 33 publications

References 38 publications

Risk factors for incident asthma and COPD in a cohort of young adults

Risk factors for incident asthma and COPD in a cohort of young adults

Factors affecting compliance and control of asthma in patients attending the Respiratory Outpatient Department, Chris Hani Baragwanath Academic Hospital

The IL6R gene polymorphisms are associated with sIL-6R, IgE and lung function in Chinese patients with asthma

Contact Info

Product

Resources

About