Since society has growing demands on young people, the mental health of adolescents is very important in the current society. This article reviews the causes, gender differences, and effects of four psychological issues among adolescents including anxiety disorders, depression, social communication disorders, and Attention deficit hyperactivity disorder (ADHD). The study reveals that among adolescents, girls are more likely than boys to experience the three mental health issues of social disorders, depression, and anxiety, while boys are more likely to experience ADHD. Moreover, this paper analyzes three areas: family, school, and government to discuss the solution for improving these issues and the current situation. Therefore, after reviewing previous literature and summarizing their findings, this paper contributes to emphasizing that girls have more probabilities to suffer from mental health problems than boys, thereby calling for society to pay more attention and offer more help to girls. Future research can work on how to reduce these conditions and propose some applicable solutions.