GENDER DIFFERENCES IN MORTALITY IN AORTIC DISSECTION &amp;ndash; RESULTS FROM THE KAISER PERMANENTE REGISTRY OF AORTIC DISSECTIONS

Brar, Somjot; Schwartz, Jaqueline; Izquierdo, Kevin M.; Lam, Cuong; Saw, Aman; Pfeffer, Thomas; Shen, Albert Yuh-Jer; Jorgensen, Michael B.; Patel, Kevin; Chen, Raymond; Vatakencherry, Geogy; Khan, Steven S.

doi:10.1016/s0735-1097(12)62080-4

Cited by 1 publication

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“…Specifically, a recent study from the Kaiser Permanente-Registry of Aortic Dissections found the 12-month mortality following diagnosis of aortic dissection to be higher in women than men (33% for women vs. 19% for men, p < 0.01). 18 Nienaber et al in a study using the international registry of aortic dissections found a higher operative mortality for women compared with men (31.9 vs. 21.9% for women and men, respectively, p ¼ 0.013). 19 However, this difference was only noted in one age group category (ages of 66-and 75year-old), while there was no difference in mortality between women and men in other age groups.…”

Section: Operative Mortalitymentioning

confidence: 94%

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Effects of Gender on Outcomes and Survival Following Repair of Acute Type A Aortic Dissection

et al. 2014

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Previous studies have demonstrated gender-related differences in early and late outcomes following type A dissection diagnosis. However, it is widely unknown whether gender affects early clinical outcomes and survival after repair of type A aortic dissection. The goal of this study was to compare the early and late clinical outcomes in women versus men after repair of acute type A aortic dissections. Between January 2000 and October 2010 a total of 251 patients from four academic medical centers underwent repair of acute type A aortic dissection. Of those, 79 were women and 172 were men with median ages of 67 (range, 20-87 years) and 58 years (range, 19-83 years), respectively (p < 0.001). Major morbidity, operative mortality, and 10-year actuarial survival were compared between the groups. Operative mortality was not significantly influenced by gender (19% for women vs. 17% for men, p = 0.695). There were similar rates of hemodynamic instability (12% for women vs. 13% men, p = 0.783) between the two groups. Actuarial 10-year survival rates were 58% for women versus 73% for men (p = 0.284). Gender does not significantly impact early clinical outcomes and actuarial survival following repair of acute type A aortic dissection.

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Section: Operative Mortalitymentioning

confidence: 94%

“…Also consistent with previous studies, women were older compared with men in our study. [18][19][20] However, these preoperative differences between women and men did not affect the operative mortality.…”

Section: Presentation and Hemodynamicsmentioning

confidence: 99%